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Zorbax HPLC Columns

Ideal for reproducible reversed-phase separations of basic compounds, neutrals, acids, peptides, and proteins. These columns are ZORBAX® Rx silica bonded to monofunctional silanes with diisobutyl or diisopropyl side groups that sterically protect key siloxane bonds from hydrolytic attack at low pH. The high-purity, low-acidity silica provides excellent peak shape with acidic, basic, and neutral compounds, making these columns ideal for low pH method development. Compatible with all common mobile phases, including very high aqueous mobile phases. Packing materials are not endcapped, allowing for maximum reproducibility under acidic mobile phase conditions. For difficult separations, these columns are stable at elevated temperatures with low pH mobile phases to enhance selectivity and maximize resolution.