XBridge Premier Columns
Particle Stability with MaxPeak HPS Protection
Working at the extremes of temperature and pH while maximizing analyte peak shape is a significant challenge for methods development scientists. Now, with XBridge Premier 2.5 µm and 3.5 µm Columns, it doesn’t have to be.
XBridge Premier Columns prevent undesired analyte/surface interactions through the power of MaxPeak HPS Technology, which is designed to increase analyte recovery, sensitivity, and reproducibility by minimizing analyte/surface interactions that can lead to sample losses.
XBridge Premier Columns are the evolution of Waters XBridge XP (eXtended Performance) columns and XBridge HPLC columns, and they combine the industry-leading column stability of Ethylene Bridged Hybrid (BEH) particles with MaxPeak High Performance Surfaces (HPS) Technology.
Protein Columns
Protein Analyses and Lab Scale Purifications
The development and successful commercialization of protein-based biopharmaceuticals and diagnostic reagents frequently depends on the ability to adequately characterize these complex biomolecules. Waters columns and methods can help solve your protein separation and characterization challenges.
Waters technology utilizes reversed-phase, ion-exchange, hydrophilic-interaction, and size-exclusion chromatography modes for peptide separation applications such as the analysis and purification of synthetic peptides, the characterization of complex proteolytic digests, and bioanalysis. These orthogonal separation techniques help provide the critical characterization data and isolated material required to produce the next generation drug.
BEH (Ethylene Bridged Hybrid) Technology
Ethylene Bridged Hybrid (BEH) particle technology ensures maximum column performance and longer column lifetimes under all chromatographic conditions. The hybrid particle technology offers many advantages over conventional silica-based particles, including the ability to control silanol activity for better reproducibility, peak shape, and efficiency. The BEH particle is created from two high purity monomers: tetraethoxysilane (TEOS) and bis(triethoxysilyl) ethane (BTEE), which results in highly stable, pH resistant, and mechanically strong particles that set the performance standard for method development. BEH particle technology allows for seamless transfer from analytical to preparative separations.