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Chemicals Evaluation and Research Institute, Japan (CERI) engages in a wide scope of activities related to chemicals, including testing, analysis, evaluations, and research and development. 

L-column series is the column for reversed-phase high-performance liquid chromatography (RP-HPLC) that enabled separation only by hydrophobic interaction because of inhibition of the secondary interaction with residual silanol groups and metal impurities. In 1990, a novel end-capping method was invented. The performance of L-column ODS developed using this method was far superior to that of existing C18 columns. L-column2 ODS, surpassing L-column ODS in performance, was developed by upgrading the end-capping method.