Superspher® is a high performance spherical silica carrier with a particle size of 4µm, providing an excellent pressure / separation performance ratio. The separation peformance of Superspher columns typically is 100,000 N/m. A broad range of modifications on Superspher are available. reversed phase derivatives (RP-8, RP-18 endcapped, RP-18, RP-18 endcapped and RP-select B) and polar derivatives (Si 60). Superspher® sorbents are packed in LiChroCART cartridges in different lenghts and internal diameters. To operate with LiChroCART cartridges, the cartridge holder manu-CART has to be used.