Automating your sample preparation with the PAL System addresses the most common challenges in the analytical lab. Key benefits include:

• Higher Throughput: Maximizes instrument uptime with unattended, 24/7 operation.
• Improved Data Quality: Reduces manual errors, leading to greater precision, reproducibility, and more reliable results.
• Enhanced Lab Safety: Minimizes human exposure to hazardous solvents and chemicals.
• Full Traceability: Every step in the process is electronically logged, ensuring a complete and auditable sample history.

When selecting an automation platform, it's crucial to look beyond your immediate needs.

Key considerations include:

• Throughput and Scalability - Does the platform offer configurations that match your current and future sample load? The PAL System scales from the single-tool RSI to the high-throughput DHR with options like LC/MS Multiplexing.
• Modularity and Flexibility - Can the system adapt to new applications? The PAL System's modular "Tool Box" design allows you to add new techniques like SPME, µSPE, or Dynamic Headspace as your lab's requirements evolve.
• Instrument Compatibility - Will it work with your existing analytical instruments? The PAL System is designed for seamless online injection and software integration with all major GC, LC, and MS vendors.

µSPE, or Micro SPE, is a miniaturized and automated Solid Phase Extraction technique that operates in two primary modes for highly efficient sample preparation:

• Pass-Through Cleanup: In this mode, the sample extract is passed through the cartridge. The sorbent is chosen to retain matrix interferences while allowing the analytes of interest to pass through for collection and analysis. This is a common approach for cleaning up complex extracts, such as in QuEChERS workflows.

• Bind-and-Elute (Enrichment): Here, the sorbent is selected to bind and retain the target analytes while the sample matrix is washed away. The purified analytes are then eluted using a small volume of a different solvent. This mode is ideal for analyte enrichment and fractionation.

The versatility of µSPE, determined by the cartridge chemistry, enables a wide range of applications, from general clean-up to targeted analysis like PFAS analysis using weak anion exchange (WAX) cartridges, or fractionation in metabolomics analysis. Key advantages are minimized solvent use, cleaner extracts without sample dilution, and improved data quality, leading to higher instrument uptime.

PAL RSI (Robotic Sample 
Injection):

PAL RTC (Robotic 
Tool Change):

PAL DHR (Dual Head Robotic):

A robust and cost-effective 
solution for reliable automated injections and basic
sample preparation. It is the 
ideal starting point
for automation and 
can be upgraded.

This model offers greater flexibility and productivity by automatically
changing tools (e.g., different
syringes, extraction tools). This
enables complex
multi-step workflows to run
unattended 24/7.

The most productive model, featuring two independent robotic heads. It can perform two
workflows simultaneously, doubling
the throughput for
high-demand applications like LC/MS multiplexing.