Biotech Knitted Open Tubular (KOT) Coils

KNITTED OPEN TUBULAR REACTION DELAY AND MIXING COILS

PRESERVED CHROMATOGRAPHIC PEAK SHAPE

The Biotech knitted open tubular (KOT) reactors are made from tubing which has been knitted into a tortuous path to force the fast moving centre of the liquid stream to mix radially with the slower moving boundary liquid layer, thereby minimizing the axial dispersion.

The shape of a chromatographic peak entering the reactor is thus preserved very efficiently. To ensure a stable radial mixing within the KOT, a linear flow rate of 10 cm/s or more is recommended. The KOT reactor is usually the most optimal delay element for use in analytical flow systems, and is typically inserted in the flow path to create a delay line, so that a reaction or other event that requires a certain time can take place.

Different delay or reaction times are accomplished by changing the inner diameter and length of the KOT, taking the flow rate through the KOT into consideration.