Chromolith Prep RP-18 Endcapped 100-25 HPLC Column, 120 A, 3 um, 25 x 100 mm - 125252

Merck Chromolith® Prep RP-18 Endcapped 100-25 HPLC Column, 120 Å, 3 µm, 25 x 100 mm

Product Number: 125252

Analytics and Sample Preparation > Analytical Chromatography > Analytical HPLC > Columns for USP Specifications > L1 Octadecylsilane, Chemically Linked to Porous Silica or Ceramic Micro Particles > Chromolith® RP-18 Endcapped > Preparative Columns

All Chromolith® columns are made of monolithic silica with a characteristic bimodal pore structure. Chromolith® 25mm columns have macropores with 3 µm diameter, giving a column efficiency exceeding 50,000 plates/meter. The mesopores are 13 nm (130 Å), the surface modification is octadecylsilan with full end-capping.

The chemical basis of Chromolith® RP-18 endcapped columns – from starting materials to surface modifications – is the same as high-end particulate columns. Thus, their selectivity is comparable to high-quality C18 endcapped reversed-phase packed columns. This allows the use of standard methods when developing new protocols. The columns are based on high-purity silica, hence they minimize the negative effect of trace metals. Furthermore, they are chemically modified with n-alkyl chains that possess a high ligand density, and fully endcapped to reduce the effect of unmodified silanol groups.

Chromolith® RP-18 endcapped 2 mm i.d. columns: Ultra-high performance on any instrument Ultra-high performance and extremely low operating pressure make Chromolith® 2 mm columns truly unique. Excellent, ultra-fast results are obtained, not only in the new UHPLC and UPLC® instruments, but equally well in all standard HPLC systems with low dead volume. Chromolith® 2 mm columns have macropores of 1.5 μm in diameter, resulting in a column efficiency that exceeds 100,000 plates/meter. The mesopores are 13 nm (130 A) in diameter, and the surface modification is octadecylsilane with full endcapping.