Chromolith Performance RP-8 Endcapped 100-4.6 HPLC Column, 130 A, 2 um, 4.6 x 100 mm - 151468

Merck Chromolith® Performance RP-8 Endcapped 100-4.6  HPLC Column, 130 Å, 2 µm, 4.6 mm I.D. x 100 mm Length

Product Number: 151468

Analytics and Sample Preparation > Analytical Chromatography > Analytical HPLC > Chromolith® HPLC Columns > Chromolith® Monolithic HPLC Columns > Chromolith® RP-8 Endcapped monolithic silica HPLC Columns > Chromolith® Performance RP-8 endcapped 100-4.6 HPLC column

Chromolith® RP-8 endcapped monolithic silica column offers high throughput, extremely long column lifetime, lower matrix sensitivity, and added column performance by column coupling. Chromolith® RP-8 endcapped column is based on a high-purity silica to reduce the negative effects of trace metals. It is chemically modified with n-alkyl chains with a high ligand density and then fully endcapped in order to reduce the effect of unmodified silanol groups. In comparison to a Chromolith® RP-18 endcapped column, a Chromolith® RP-8 endcapped column offers a better retention for hydrophobic compounds. The Chromolith® RP-8 endcapped column is available in the dimension 100-4.6 mm.

The chemical basis of Chromolith® RP-18 endcapped columns – from starting materials to surface modifications – is the same as high-end particulate columns. Thus, their selectivity is comparable to high-quality C18 endcapped reversed-phase packed columns. This allows the use of standard methods when developing new protocols. The columns are based on high-purity silica, hence they minimize the negative effect of trace metals. Furthermore, they are chemically modified with n-alkyl chains that possess a high ligand density, and fully endcapped to reduce the effect of unmodified silanol groups.

Chromolith® RP-18 endcapped 2 mm i.d. columns: Ultra-high performance on any instrument Ultra-high performance and extremely low operating pressure make Chromolith® 2 mm columns truly unique. Excellent, ultra-fast results are obtained, not only in the new UHPLC and UPLC® instruments, but equally well in all standard HPLC systems with low dead volume. Chromolith® 2 mm columns have macropores of 1.5 μm in diameter, resulting in a column efficiency that exceeds 100,000 plates/meter. The mesopores are 13 nm (130 A) in diameter, and the surface modification is octadecylsilane with full endcapping.