Ligand Exchange Columns
Daicel CHIRALPAK® WH and CHIRALPAK® MA(+) contain proline and N,N-dioctyl-L-alanine as their chiral selectors. They are ligand exchange type columns that can be used with aqueous solutions of copper sulfate. These columns were designed for alpha amino acids and other acidic chiral molecules.
CHIRALPAK® WH and MA(+) columns The chiral stationary phases in these columns are made of amino acids and its derivatives coated or bonded to silica supports (with a particle size of 10µm for WH and 3µm for MA(+)). Since these columns are ligand-exchange type columns, the standard mobile phase to use is an aqueous solution of CuSO4 (0.1 to 2mM). These columns can tolerate organic modifiers such as Methanol and Acetonitrile according to the specifications in the instruction manual.
Separation compounds
- Amino acids and amino acid derivatives
- Hydroxycarbonic acids
