Dr. Maisch Exsil 300 C18M, 5 µm, 300 Å, 0.1 g bulk material for HPLC Columns - 5136748

ExSil® 300

Dr. Maisch Exsil 300 C18M, 5µm, 300Å, 0.1g bulk material for HPLC Columns

Product Number: 5136748

• Alternative to Vydac TP phases
• Pore Size: 300(+/-10) Å
• Pore Volume: 0.78 ml/g
• Surface Area: 100 m2/g
• Particle sizes: 3, 5 and 10 μm
• Phases: Silica, C4, C8, C18, PAH and HAAX
• Exsil 300: Columns with a pore size of 300 Å Angstroms (30 nm)

These columns are characterized by their ability to retain and separate compounds based on their hydrophobicity, with the C18 designation indicating the presence of a long (18-carbon) hydrocarbon chain on the stationary phase. Exsil C18 columns are designed to offer high performance and are often used as an alternative when other C18 columns fail to deliver desired results.

• Reversed-Phase Chromatography: The C18 column utilizes a reversed-phase mechanism, where non-polar analytes are retained by the non-polar C18 stationary phase and eluted with a polar mobile phase.
• C18 Stationary Phase: The stationary phase consists of silica particles with octadecylsilyl (C18) groups attached, creating a hydrophobic surface.
• Diametric Selectivity: Exsil C18 columns are designed to have different selectivity compared to standard C18 phases, potentially providing better separation for challenging samples.
• High Polarity and Base Retention: They are designed for high polarity reversed-phase applications and offer high retention of basic compounds, which can be beneficial for mass spectrometry detection.
• MS Compatibility: Exsil C18 columns are compatible with mass spectrometry, making them suitable for analytical workflows that involve both chromatographic separation and mass spectrometric detection.
• Separation of Hydrophobic Compounds: They are particularly useful for separating non-polar and moderately polar compounds due to their strong hydrophobic interactions.