Amaze SPF is a stationary phase with an alkyl chain and two polyfluorinated aromatic rings as a “sandwich-type” stationary phase ligand. The stationary phase has several polar-embedded groups for enhanced selectivity and better stability in highly aqueous mobile phases. Highly reproducible and stable in 100% organic and 100% water. Two polyfluorinated rings show a unique selectivity compared to single ring columns like Amaze PFP and Amaze AR as well as traditional reversed-phase and i-pi columns. Designed to separate aromatic compounds based on specific pi-pi interaction between analytes and two substituted aromatic rings. Suitable for separation of structural isomers of aromatic compounds. Retains hydrophobic non-aromatic compounds based on pure reversed-phase interactions. Interact differently with analytes with electron-withdrawing and electron-donating groups. Available in 3, 5, and 10 um particles.