LiChrospher® ADS
Inner Diameter (I.D.): 2 mm
Length: 25 mm
Package Contents: 1 Cartridge
LiChrospher® ADS allows the direct extraction and enrichment of hydrophobic, low molecular weight analytes from
untreated samples such as haemolysed blood, plasma, serum, milk, salivary fluid, fermentation broth, supernatants
of cell cultures and tissue as well as food homogenates.
LiChrospher® ADS sorbents belong to the family of restricted access materials (RAM) with two chemically different
surfaces, a hydrophilic external surface and a hydrophobic inner surface. Extraction and fractionation is based on
the simultaneous performance of two chromatographic processes: reversed phase/ion-pair chromatography and size
exclusion chromatography.
Benefits of LiChrospher® ADS
- Saves money and time: The high amount of analysis cycles, the direct injection of untreated biological fluids, and the fully automated system, extends column lifetime as well as saving time significantly
- Improved precision, accuracy, and sensitivity
- Quantitative elimination of protein matrix
- On-column enrichment of analytes
With LiChroCART® cartridges the user works with re-usable endfittings which fit different cartridge lengths.
Since these cartridge holders may remain in the system and the capillary connections do not need to be detached,
the cartridges may be changed within the shortest possible time. Changing a separation cartridge from a length
of 125 to 250 mm and back presents no problems. Furthermore, the adaptation of internal diameter (3 mm or 2 mm)
to the analysis problem is possible within a few minutes. The endfittings are designed to allow the cartridges to be
hand-sealed at normal working pressures of 150 to 200 bar without the need for any tools. Only at higher pressures
may further tightening with a wrench become necessary.
Specifications of LiChrospher® ADS
Sorbent characteristic: Spherical silica gel particles with two chemical different surface modifications
Surface modifications: 1. Exterior surface | 2. Interior surface (surface of pores) | DIOL modification | C-4, C-8, or C-18 modification
ADS: Alkyl-DIOL-Silica
Particle size: 25 μm
Pore diameter: 60 Å (6 nm)
Stability: pH 2-7.5
- Model: 1.50386.0001
- Manufactured by: Merck Chemicals