COSMOSIL Diol-120-II, Diol-300-II and Diol-1000-II gel filtration columns are ideal for the size-based separation of proteins and other water soluble polymers. The separation MW range is 5,000-700,000 daltons for proteins and 1000-500,000 daltons for water soluble polymers when Diol-120-II, Diol-300-II and Diol-1000-II are used in series.
- Ideal for the size-based separation of proteins and water soluble polymers
- Reduce undesirable adsorption
- Separate large hydrophilic molecules, such as proteins, polysaccharides and nucleic
acids, by molecular size - Reduce undesirable adsorption
- High pressure tolerance with silica gel-based packing material
- Different products cover a wide range of molecular weight
| Packing Material | 5Diol-120-II | 5Diol-300-II | 5Diol-1000-II | 5Diol-2000-II |
|---|---|---|---|---|
| USP code | L20 | |||
| Silica Gel | High purity porous spherical silica * | |||
| Average Particle Size | 5 µm | |||
| Average Pore Size | approx. 120Å | approx. 300Å | approx. 1000Å | approx. 2000Å |
| Stationary Phase | Diol group | |||
| Suitable Samples | Protein, Water-Soluble Polymer | |||
| Flow Rate | 0.5-1.0 ml/min | |||
| Selection of Pore Size (Proteins) | 5,000-100,000 | 10,000-700,000 | - | - |
| Selection of Pore Size (Water Soluble Polymer) | 1,000-20,000 | 5,000-100,000 | 50,000-500,000 | - |
