Nacalai Tesque COSMOSIL 5CN-MS Analytical HPLC Column, 5 µm, 120 Å, 4.6 x 250 mm, 1/Pk - 38236-31

Cosmosil® CN-MS

Nacalai Tesque COSMOSIL 5CN-MS Analytical HPLC Column, 5µm, 120Å, 4.6mm I.D. x 250mm Length, 1/Pk

Product Number: 38236-31

Alkyl chain columns - Cyanopropyl group - Monomeric

COSMOSIL alkyl type columns are columns that bond C22 (docosyl group), C8 (octyl group), C4 (butyl group), and TMS (triethyl group) to the packing material. The retention order of samples on the column according to the lipophilic effect is C22=C18>C8>C4>TMS. Columns with lipophilic effect lower than C18 or C22 are effective in separating highly lipophilic compounds or compounds with lipophilic structures that are very different from each other. The lipophilicity of C22 is the same as that of C18. However, the stereoselectivity of C22 is higher than that of C18.

Gradient elution is commonly used for the samples containing both polar and non-polar compounds. However, gradient elution may cause reproducibility problem depending on the gradient mixer and pump, and need an equilibration time for each analysis. COSMOSIL 5CN-MS offers rapid analysis and great reproducibility using isocratic elution mode.

• Cyanopropyl group bonded stationary phase
• Enables separation of different hydrophobic samples without using gradient
• For separation of natural compounds with different hydrophobicity

Reversed Phase HPLC Columns:

Column Specifications:

Additional Column Sizes are available - Please contact our Sales Team with your requirements.

Cosmosil Columns Online Catalogue:

• Nacalai Tesque COSMOSIL HPLC Columns
• Nacalai Tesque COSMOCORE UHPLC Columns
• Nacalai Tesque Reagents, Standards, Solvents