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Cosmosil® TMS-MS
Nacalai Tesque COSMOSIL 5TMS-MS Semi-preparative HPLC Guard Column, 5µm, 120Å, 10mm I.D. x 20mm Length, 1/Pk
Product Number: 38172-61
Alkyl chain columns - Trimethyl group - Monomeric
COSMOSIL alkyl type columns are columns that bond C22 (docosyl group), C8 (octyl group), C4 (butyl group), and TMS (triethyl group) to the packing material. The retention order of samples on the column according to the lipophilic effect is C22=C18>C8>C4>TMS. Columns with lipophilic effect lower than C18 or C22 are effective in separating highly lipophilic compounds or compounds with lipophilic structures that are very different from each other. The lipophilicity of C22 is the same as that of C18. However, the stereoselectivity of C22 is higher than that of C18.
Reversed Phase HPLC Columns:
| PFP | CN-MS | C22-AR-II | C8-MS | |
| Silica Gel | High purity porous spherical silica | |||
| Average Particle Size | 5 µm | |||
| Average Pore Size | approx. 120 Å | |||
| Specific Surface Area | approx. 300 m2/g | |||
| Bonded Phase | Cyanopropyl group | Dococyl group | Octyl group | |
| Bonding Type | Monomeric | Polymeric | Monomeric | |
| Main Interaction | Hydrophobic interaction Dipole-dipole | Hydrophobic interaction | ||
| End-capping Treatment | Near-perfect Treatment | |||
| Carbon Load | approx. 10% | approx. 7% | approx. 19% | approx. 10% |
| pH Range | 2-7.5 | |||
| C4-MS | TMS-MS | PE-MS | ||
| Silica Gel | High purity porous spherical silica | |||
| Average Particle Size | 5 µm | |||
| Average Pore Size | approx. 120 Å | |||
| Specific Surface Area | approx. 300 m2/g | |||
| Bonded Phase | Butyl group | Trimethyl group | Phenylethyl group | |
| Bonding Type | Monomeric | |||
| Main Interaction | Hydrophobic interaction | Hydrophobic interaction Dipole-dipole | ||
| End-capping Treatment | Near-perfect Treatment | |||
| Carbon Load | approx. 7% | approx. 5% | approx. 10% | |
| pH Range | 2-7.5 | |||
Column Specifications:
| Product Description | COSMOSIL 5C4-MS Guard Column (10.0 mm I.D. x 20 mm) |
|---|---|
| Quantity | 1 pc |
| Manufacturer | Nacalai Tesque |
| Product Type | HPLC Guard Column |
| Length | 20 mm |
| Internal Diameter | 10.0 mm |
| Particle Size | 5 µm |
| Chemistry | Trimethyl |
| Chemistry Producers Term | TMS-MS |
| Pore Size | 120 Å |
| USP Class | L13 |
| Carbon Load | 7.0 % |
| Bet Surface Area [m2/g] | 300.0 |
| Endcapping | End-Fitting: Waters type |
| Column Type | Semi-preparative Guard Column |
| Hardware Material | Stainless Steel |
| Hardware Type | Ready-to-use Column |
| pH Minimum | 2.0 |
| pH Maximum | 7.5 |
| Mode of Separation | Reversed Phase Chromatography (RP) |
| Technology | High-Performance Liquid Chromatography (HPLC) |
| Matrix | Silica |
| Particle Morphology | spherical, fully porous |
Additional Column Sizes are available - Please contact our Sales Team with your requirements.
Cosmosil Columns Online Catalogue:
- Nacalai Tesque COSMOSIL HPLC Columns
- Nacalai Tesque COSMOCORE UHPLC Columns
- Nacalai Tesque Reagents, Standards, Solvents
- Model: 38172-61
- Manufactured by: Nacalai Tesque
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