Suitable in Either Reversed Phase or Normal Phase Mode
Shim-pack GIS CN is capable of either normal phase or reversed phase analysis. Cyanopropryl groups bonded to silica gel with high density increases the difference recognition of hydrophilicity and the stability. Due to no end-capping, it is capable of analysis utilizing cyano group characteristics. In reversed phase mode, separation can be achieved for those compounds that could not be separated on straight-chain-alkyl columns, such as C18 or C8 bonded phases. When using the column for reversed phase mode, fully equilibrate the column before use.
| Shim-pack GISS | Shim-pack GIS | ||||||
| Reversed Phase | Reversed Phase | Normal Phase/RP | HILIC | ||||
| Chemistry | C18 | C18 | C18-P | RP-Shield | CN | SIL | HILIC |
| Bonded Phase | Octadecyl groups | Octadecyl groups | Octadecyl groups | Octadecyl groups | Cyanopropryl groups | - | Diol groups |
| Features | High speed analysis with ultra-high inertness and high stability |
High retentivity, lower column back pressure, high inertness |
High steric selectivity | Embedded with a polar functional group |
Suitable in either reversed phase or normal phase mode |
Suitable in either reversed phase or normal phase mode |
deal for the separation of highly polar basic compounds |
| Particle Size (µm) | 1.9, 3, 5 | 2, 3, 4, 5, 10 | 3, 5 | 5 | 3, 5 | 3, 5 | 3, 5 |
| Pore Size | 20 nm 200 Å |
10 nm 100 Å |
10 nm 100 Å |
10 nm 100 Å |
10 nm 100 Å |
10 nm 100 Å |
10 nm 100 Å |
| Surface Area (m2/g) | 200 | 450 | 450 | 450 | 450 | 450 | 450 |
| Carbon Loading (%) | 9 | 15 | 29 | 9 | 14 | - | 20 |
| End Cap | Yes | Yes | No | No | No | No | No |
| pH Range | 1-10 | 2-7.5 | 2-7.5 | 2-7.5 | 2-7.5 | 2-7.5 | 2-7.5 |
| USP Code | L1 | L1 | L1 | L1 | L10 | L3 | L20 |
