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VDS optilab Eurospher

Eurospher columns are highly-regarded HPLC and UHPLC stationary phases primarily manufactured by KNAUER. Built on ultra-pure, fully porous spherical silica, they are widely used in analytical, preparative, and process-scale separations across pharmaceutical, chemical, and biological applications.

  • C18: The standard reversed-phase column (USP L1) with ∼16% carbon load.
  • C18 A: Polar-endcapped C18 phase allowing 100% aqueous eluents for polar compounds.
  • C18 P: Maximum carbon load for extreme steric selectivity and pH stability.
  • C18 H: A general reversed-phase ideal for acidic, basic, and neutral analytes.
  • NH₂: Aminopropyl modification for Normal Phase, HILIC, and Ion Chromatography.
  • HILIC: Zwitterionic phase designed to retain hydrophilic and ionic analytes.

Eurospher I: The legacy 2nd-generation silica-based columns, remaining a reliable staple for routine tasks

Eurospher C18 (and its modern counterpart, Eurospher II C18) is a highly popular reversed-phase High-Performance Liquid Chromatography (HPLC) column produced by KNAUER. It is widely considered a "workhorse" for routine analytical and preparative separations of acidic, basic, and neutral analytes.

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