Waters Xevo G3 QTof Quadrupole Time-of-Flight Mass Spectrometer

Xevo G3 QTof

Please contact our Sales Team for a quote.

Complete coverage for confident characterization

Maximize sample information for your analytes from detailed characterization to accurate quantitation with the Xevo G3 QTof, which enables complete confidence in your results.

The latest generation of the Xevo product line extends the simplicity and range of characterization, from challenging small molecules to complex biotherapeutics. Updates to the ion optics design provide consistent robustness and performance, with incorporation of core technology for comprehensive quantitation capabilities. Centered around an expanding array of informatics tools, the Xevo G3 QTof has your lab covered.

Overview

• Ultimate performance: Ensure maximum coverage of analytes, with improved transmission of low mass labile species, while still excelling in traditional biopharmaceutical workflows and addressing emerging needs to characterize new modalities. 
• Connected productivity: Harmonize workflows across development, manufacturing and monitoring/quality control (QC) with the waters_connect ecosystem, Xevo G3 QTof, and BioAccord System with ACQUITY Premier. 
• Extended flexibility: Improve quantitative capabilities, with wider inter- and intra-spectrum dynamic range for comprehensive quantitative/qualitative analysis, ideal for screening and targeted applications. 
• Unquestioned confidence: Achieve consistent data quality and reproducibility to maintain performance and productivity over a longer time period, with updated ion optics.

Recommended Use: Characterize and quantify a diverse set of molecules on a single, analytical workhorse.

Ultimate performance for a range of analytes

Demand more from your analytical systems to extend the capabilities of your lab. The Xevo G3 QTof incorporates new technology building blocks that improve the ability to characterize complex biologics (with the inclusion of a m/z 16,000 calibration range and tailored informatics) while enhancing the analysis of challenging small molecules (with updates to the ion optics and detection system to maximize transmission and dynamic range). The Xevo G3 QTof, equipped with the StepWave XS, efficiently transmits low mass, labile species – enabling you to increase compound coverage and analytical fidelity.

Xevo G3 QTof provides significant increase in sensitivity for challenging labile compounds

Connected productivity for harmonized workflows

Harmonizing workflows across development, manufacturing, and QC is key to ensuring lab productivity. The Xevo G3 QTof is ideal for characterizing biomolecules and processes before transitioning to dedicated attribute monitoring assays on the Xevo G3 QTof or BioAccord System with ACQUITY Premier. The waters_connect ecosystem offers seamless, compliance-ready workflows to understand and monitor biotherapeutic variation. Systems and users are connected through waters_connect with security-controlled access, full data traceability, and the operational efficiency and scalability of networked deployment. 

Harmonize your workflows across development, manufacturing, and QC with waters_connect at the core.

Delivering qualitative and quantitative performance

Maximize system usage with a flexible multifunctional instrument that delivers high-quality quantitative and qualitative data sets. The Xevo G3 QTof has evolved to specifically address these needs, with updates to core technology delivering up to 5 orders of linear dynamic range for targeted analysis.

For untargeted and screening experiments, the Xevo G3 QTof can detect and quantify components of interest in the most challenging complex matrices with up to 4x increase in-spectrum dynamic range.

Demonstrating 5 orders of linear dynamic range in Tof-MRM mode

Unquestioned confidence with consistent robustness and reproducibility

Instrument stability and uptime is an unquestioned necessity in a fast-paced, high-throughput environments. The evolved design of the Xevo G3 QTof has been engineered to deliver consistent robustness and reproducibility, maintaining performance and productivity over a longer time period. With updated ion optics design and optimized ion beam conditioning, the Xevo G3 QTof is a true analytical workhorse that reliably and routinely delivers high-quality data.

Minimize contamination and increase uptime with optimized ion optics.