NUCLEOSIL® CN/CN-RP HPLC Columns

Polar to mid-polar cyano (nitrile) modified silica for reversed phase and normal phase chromatography:
Normal phase: with low-polarity solvents for many compounds, which can also be separated on unmodified silica, however, due to the rapid equilibration much more suitable for gradient separations
Reversed phase: with different selectivity than C18, C8 or phenyl modified packings

Available pore sizes 100, 120, 300 and 500 Å, available particle sizes 5 µm, 7 µm and 10 µm, 
pH stability at 20 °C: 2–8; carbon content 5 % for 100 Å pores, ~ 3 % for 120 Å pores

Separation mechanism based on π–π interactions, polar interactions and hydrophobic interactions

Corresponding NUCLEODUR® phase see NUCLEODUR® CN / CN-RP