NUCLEOSIL® is a family of totally porous spherical silicas with a very pure and uniform SiO2 structure
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wide acceptance as routine packings for very different fields of chromatography
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one of the first spherical silicas used in HPLC
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developed in the early seventies, it became a world-renowned HPLC packing
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still found in many analytical and preparative applications
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an absolutely reliable choice in HPLC
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the largest variety of modified HPLC silicas available on the market
Summary of available NUCLEOSIL® phasesPhase | Modification | Formula |
RP phases |
NUCLEOSIL® C18 | medium density octadecyl, endcapped | -(CH2)17-CH3 |
NUCLEOSIL® C18 AB | crosslinked octadecyl, endcapped, high steric selectivity | -(CH2)17-CH3 |
NUCLEOSIL® C18 HD | high density octadecyl, endcapped | -(CH2)17-CH3 |
NUCLEOSIL® C18 Nautilus | hydrophilic octadecyl, embedded polar group, endcapped | -(CH2)17-CH3 |
NUCLEOSIL® Protect I | special RP phase with protective polar group, endcapped |
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NUCLEOSIL® C8ec | medium density octyl, endcapped | -(CH2)7-CH3 |
NUCLEOSIL® C8 | standard octyl, not endcapped | -(CH2)7-CH3 |
NUCLEOSIL® C8 HD | high density octyl, endcapped | -(CH2)7-CH3 |
NUCLEOSIL® C4 | medium density butyl, endcapped | -(CH2)3-CH3 |
NUCLEOSIL® C2 | dimethyl | -(CH3)2 |
NUCLEOSIL® C6H5 ec | medium density phenyl, endcapped | -(CH2)3-C6H5 |
NUCLEOSIL® C6H5 | standard phenyl, not endcapped | -(CH2)3-C6H5 |
Polar phases |
NUCLEOSIL® CN | cyanopropyl (nitrile) | -(CH2)3-CN |
NUCLEOSIL® NO2 | nitrophenyl | -(CH2)3-C6H4-NO2 |
NUCLEOSIL® OH | diol (dihydroxypropyl) | -(CH2)3-O-CH2-CH(OH)-CH2OH |
NUCLEOSIL® NH2 | aminopropyl | -(CH2)3-NH2 |
NUCLEOSIL® N(CH3)2 | dimethylamino | -(CH2)3-N(CH3)2 |
NUCLEOSIL® SA | benzenesulphonic acid, strongly acidic cation exchanger (SCX) | -(CH2)3-C6H4-SO3Na |
NUCLEOSIL® SB | quaternary ammonium, strongly basic anion exchanger (SAX) | -(CH2)3-C6H4-CH2-N+(CH3)3Cl– |
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NUCLEOSIL® SiOH | unmodified | (SiO2)n |