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COSMOSIL Hydrophilic Interaction HILIC Columns

Hydrophilic interaction chromatography is a variation of normal phase chromatography in which a polar stationary phase is used with a mobile phase that contains a high concentration of water-miscible organic solvent and a low concentration of aqueous eluent. The main retention mechanism is the partitioning of the polar analytes between the polar stationary and the non-polar mobile phase. As it is also called "aqueous normal phase," the elution order is similar to that of normal phase and the sample elution is in the order of increasing hydrophilicity. Without using ion-pair reagents, COSMOSIL HILIC retains highly polar analytes that would not be retained in reversed phase chromatography. It also shows a weak anion-exchange mechanism with the positively charged stationary phase; thus acidic compounds are strongly retained.

  • Triazole-bonded stationary phase
  • Enhanced hydrophilic interaction
  • Excellent retention for highly polar analytes
  • Unique anion-exchange mechanism
Packing MaterialHILIC
Silica GelHigh purity porous spherical silica
Average Particle Size5 µm
USP CodeL104
Specific Surface Areaapprox. 300 m2/g
InteractionsHydrophilic Interaction, Anion Exchange
Suitable SamplesHydrophilic Compounds, Acidic Compounds
FeaturesSuitable for non-retaining by C18


Item Name Product Image Price

Nacalai Tesque COSMOSIL 2.5HILIC Analytical UHPLC Column, 2.5 µm, 130 Å, 3 x 100 mm, 1/Pk - 11773-21

Cosmosil® 2.5HILIC Nacalai Tesque COSMOSIL 2.5HILIC Analytical UHPLC Column, 2.5µm, 130Å, 3mm I.D. x 100mm Length, 1/Pk Product Number: 11773-21 Ultra-High Performance Column for HILIC Hydrophilic Interaction Analysis Hydrophilic interaction...
Nacalai Tesque COSMOSIL 2.5HILIC Analytical UHPLC Column, 2.5 µm, 130 Å, 3 x 100 mm, 1/Pk - 11773-21 £381.00Buy Now

Nacalai Tesque COSMOSIL 2.5HILIC Analytical UHPLC Column, 2.5 µm, 130 Å, 3 x 150 mm, 1/Pk - 11774-11

Cosmosil® 2.5HILIC Nacalai Tesque COSMOSIL 2.5HILIC Analytical UHPLC Column, 2.5µm, 130Å, 3mm I.D. x 150mm Length, 1/Pk Product Number: 11774-11 Ultra-High Performance Column for HILIC Hydrophilic Interaction Analysis Hydrophilic interaction...
Nacalai Tesque COSMOSIL 2.5HILIC Analytical UHPLC Column, 2.5 µm, 130 Å, 3 x 150 mm, 1/Pk - 11774-11 £381.00Buy Now

Nacalai Tesque COSMOSIL 2.5HILIC Analytical UHPLC Column, 2.5 µm, 130 Å, 3 x 50 mm, 1/Pk - 11771-41

Cosmosil® 2.5HILIC Nacalai Tesque COSMOSIL 2.5HILIC Analytical UHPLC Column, 2.5µm, 130Å, 3mm I.D. x 50mm Length, 1/Pk Product Number: 11771-41 Ultra-High Performance Column for HILIC Hydrophilic Interaction Analysis Hydrophilic interaction...
Nacalai Tesque COSMOSIL 2.5HILIC Analytical UHPLC Column, 2.5 µm, 130 Å, 3 x 50 mm, 1/Pk - 11771-41 £381.00Buy Now

Nacalai Tesque COSMOSIL 2.5HILIC Analytical UHPLC Column, 2.5 µm, 130 Å, 3 x 75 mm, 1/Pk - 11772-31

Cosmosil® 2.5HILIC Nacalai Tesque COSMOSIL 2.5HILIC Analytical UHPLC Column, 2.5µm, 130Å, 3mm I.D. x 75mm Length, 1/Pk Product Number: 11772-31 Ultra-High Performance Column for HILIC Hydrophilic Interaction Analysis Hydrophilic interaction...
Nacalai Tesque COSMOSIL 2.5HILIC Analytical UHPLC Column, 2.5 µm, 130 Å, 3 x 75 mm, 1/Pk - 11772-31 £381.00Buy Now

Nacalai Tesque COSMOSIL 2.5HILIC Microbore Analytical UHPLC Column, 2.5 µm, 130 Å, 2 x 100 mm, 1/Pk - 11769-91

Cosmosil® 2.5HILIC Nacalai Tesque COSMOSIL 2.5HILIC Microbore Analytical UHPLC Column, 2.5µm, 130Å, 2mm I.D. x 100mm Length, 1/Pk Product Number: 11769-91 Ultra-High Performance Column for HILIC Hydrophilic Interaction Analysis Hydrophilic...
Nacalai Tesque COSMOSIL 2.5HILIC Microbore Analytical UHPLC Column, 2.5 µm, 130 Å, 2 x 100 mm, 1/Pk - 11769-91 £381.00Buy Now

Nacalai Tesque COSMOSIL 2.5HILIC Microbore Analytical UHPLC Column, 2.5 µm, 130 Å, 2 x 150 mm, 1/Pk - 11770-51

Cosmosil® 2.5HILIC Nacalai Tesque COSMOSIL 2.5HILIC Microbore Analytical UHPLC Column, 2.5µm, 130Å, 2mm I.D. x 150mm Length, 1/Pk Product Number: 11770-51 Ultra-High Performance Column for HILIC Hydrophilic Interaction Analysis Hydrophilic...
Nacalai Tesque COSMOSIL 2.5HILIC Microbore Analytical UHPLC Column, 2.5 µm, 130 Å, 2 x 150 mm, 1/Pk - 11770-51 £381.00Buy Now

Nacalai Tesque COSMOSIL 2.5HILIC Microbore Analytical UHPLC Column, 2.5 µm, 130 Å, 2 x 50 mm, 1/Pk - 11766-21

Cosmosil® 2.5HILIC Nacalai Tesque COSMOSIL 2.5HILIC Microbore Analytical UHPLC Column, 2.5µm, 130Å, 2mm I.D. x 50mm Length, 1/Pk Product Number: 11766-21 Ultra-High Performance Column for HILIC Hydrophilic Interaction Analysis Hydrophilic...
Nacalai Tesque COSMOSIL 2.5HILIC Microbore Analytical UHPLC Column, 2.5 µm, 130 Å, 2 x 50 mm, 1/Pk - 11766-21 £381.00Buy Now

Nacalai Tesque COSMOSIL 2.5HILIC Microbore Analytical UHPLC Column, 2.5 µm, 130 Å, 2 x 75 mm, 1/Pk - 11768-01

Cosmosil® 2.5HILIC Nacalai Tesque COSMOSIL 2.5HILIC Microbore Analytical UHPLC Column, 2.5µm, 130Å, 2mm I.D. x 75mm Length, 1/Pk Product Number: 11768-01 Ultra-High Performance Column for HILIC Hydrophilic Interaction Analysis Hydrophilic...
Nacalai Tesque COSMOSIL 2.5HILIC Microbore Analytical UHPLC Column, 2.5 µm, 130 Å, 2 x 75 mm, 1/Pk - 11768-01 £381.00Buy Now

Nacalai Tesque COSMOSIL HILIC Microbore Analytical HPLC Column, 5 µm, 120 Å, 1 x 150 mm, 1/Pk - 07869-11

Cosmosil® HILIC Nacalai Tesque COSMOSIL HILIC Microbore Analytical HPLC Column, 5µm, 120Å, 1mm I.D. x 150mm Length, 1/Pk Product Number: 07869-11 HPLC Column for Hydrophilic Interaction Hydrophilic interaction chromatography is a variation of...
Nacalai Tesque COSMOSIL HILIC Microbore Analytical HPLC Column, 5 µm, 120 Å, 1 x 150 mm, 1/Pk - 07869-11 £432.00Buy Now

Nacalai Tesque COSMOSIL HILIC Microbore Analytical HPLC Column, 5 µm, 120 Å, 1 x 250 mm, 1/Pk - 07870-71

Cosmosil® HILIC Nacalai Tesque COSMOSIL HILIC Microbore Analytical HPLC Column, 5µm, 120Å, 1mm I.D. x 250mm Length, 1/Pk Product Number: 07870-71 HPLC Column for Hydrophilic Interaction Hydrophilic interaction chromatography is a variation of...
Nacalai Tesque COSMOSIL HILIC Microbore Analytical HPLC Column, 5 µm, 120 Å, 1 x 250 mm, 1/Pk - 07870-71 £504.00Buy Now

Nacalai Tesque COSMOSIL HILIC Analytical HPLC Guard Column, 5 µm, 120 Å, 2 x 10 mm, 1/Pk - 07569-41

Cosmosil® HILIC Nacalai Tesque COSMOSIL HILIC Analytical HPLC Guard Column, 5µm, 120Å, 2.0mm I.D. x 10mm Length, 1/Pk Product Number: 19184-14 HPLC Column for Hydrophilic Interaction Hydrophilic interaction chromatography is a variation of...
Nacalai Tesque COSMOSIL HILIC Analytical HPLC Guard Column, 5 µm, 120 Å, 2 x 10 mm, 1/Pk - 07569-41
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Nacalai Tesque COSMOSIL HILIC Microbore Analytical HPLC Column, 5 µm, 120 Å, 2 x 100 mm, 1/Pk - 08569-11

Cosmosil® HILIC Nacalai Tesque COSMOSIL HILIC Microbore Analytical HPLC Column, 5µm, 120Å, 2mm I.D. x 100mm Length, 1/Pk Product Number: 08569-11 HPLC Column for Hydrophilic Interaction Hydrophilic interaction chromatography is a variation of...
Nacalai Tesque COSMOSIL HILIC Microbore Analytical HPLC Column, 5 µm, 120 Å, 2 x 100 mm, 1/Pk - 08569-11 £325.00Buy Now

Nacalai Tesque COSMOSIL HILIC Microbore Analytical HPLC Column, 5 µm, 120 Å, 2 x 150 mm, 1/Pk - 07054-71

Cosmosil® HILIC Nacalai Tesque COSMOSIL HILIC Microbore Analytical HPLC Column, 5µm, 120Å, 2mm I.D. x 150mm Length, 1/Pk Product Number: 07054-71 HPLC Column for Hydrophilic Interaction Hydrophilic interaction chromatography is a variation of...
Nacalai Tesque COSMOSIL HILIC Microbore Analytical HPLC Column, 5 µm, 120 Å, 2 x 150 mm, 1/Pk - 07054-71 £387.00Buy Now

Nacalai Tesque COSMOSIL HILIC Microbore Analytical HPLC Column, 5 µm, 120 Å, 2 x 250 mm, 1/Pk - 07489-91

Cosmosil® HILIC Nacalai Tesque COSMOSIL HILIC Microbore Analytical HPLC Column, 5µm, 120Å, 2mm I.D. x 250mm Length, 1/Pk Product Number: 07489-91 HPLC Column for Hydrophilic Interaction Hydrophilic interaction chromatography is a variation of...
Nacalai Tesque COSMOSIL HILIC Microbore Analytical HPLC Column, 5 µm, 120 Å, 2 x 250 mm, 1/Pk - 07489-91 £437.00Buy Now

Nacalai Tesque COSMOSIL HILIC Microbore Analytical HPLC Column, 5 µm, 120 Å, 2 x 30 mm, 1/Pk - 08568-21

Cosmosil® HILIC Nacalai Tesque COSMOSIL HILIC Microbore Analytical HPLC Column, 5µm, 120Å, 2mm I.D. x 30mm Length, 1/Pk Product Number: 08568-21 HPLC Column for Hydrophilic Interaction Hydrophilic interaction chromatography is a variation of...
Nacalai Tesque COSMOSIL HILIC Microbore Analytical HPLC Column, 5 µm, 120 Å, 2 x 30 mm, 1/Pk - 08568-21 £314.00Buy Now

Nacalai Tesque COSMOSIL HILIC Microbore Analytical HPLC Column, 5 µm, 120 Å, 2 x 50 mm, 1/Pk - 07052-91

Cosmosil® HILIC Nacalai Tesque COSMOSIL HILIC Microbore Analytical HPLC Column, 5µm, 120Å, 2mm I.D. x 50mm Length, 1/Pk Product Number: 07052-91 HPLC Column for Hydrophilic Interaction Hydrophilic interaction chromatography is a variation of...
Nacalai Tesque COSMOSIL HILIC Microbore Analytical HPLC Column, 5 µm, 120 Å, 2 x 50 mm, 1/Pk - 07052-91
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Nacalai Tesque COSMOSIL HILIC Analytical HPLC Column, 5 µm, 120 Å, 3 x 100 mm, 1/Pk - 09193-91

Cosmosil® HILIC Nacalai Tesque COSMOSIL HILIC Analytical HPLC Column, 5µm, 120Å, 3mm I.D. x 100mm Length, 1/Pk Product Number: 09193-91 HPLC Column for Hydrophilic Interaction Hydrophilic interaction chromatography is a variation of normal...
Nacalai Tesque COSMOSIL HILIC Analytical HPLC Column, 5 µm, 120 Å, 3 x 100 mm, 1/Pk - 09193-91
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Nacalai Tesque COSMOSIL HILIC Analytical HPLC Column, 5 µm, 120 Å, 3 x 150 mm, 1/Pk - 07871-61

Cosmosil® HILIC Nacalai Tesque COSMOSIL HILIC Analytical HPLC Column, 5µm, 120Å, 3mm I.D. x 150mm Length, 1/Pk Product Number: 07871-61 HPLC Column for Hydrophilic Interaction Hydrophilic interaction chromatography is a variation of normal...
Nacalai Tesque COSMOSIL HILIC Analytical HPLC Column, 5 µm, 120 Å, 3 x 150 mm, 1/Pk - 07871-61
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Nacalai Tesque COSMOSIL HILIC Analytical HPLC Column, 5 µm, 120 Å, 3 x 250 mm, 1/Pk - 07872-51

Cosmosil® HILIC Nacalai Tesque COSMOSIL HILIC Analytical HPLC Column, 5µm, 120Å, 3mm I.D. x 250mm Length, 1/Pk Product Number: 07872-51 HPLC Column for Hydrophilic Interaction Hydrophilic interaction chromatography is a variation of normal...
Nacalai Tesque COSMOSIL HILIC Analytical HPLC Column, 5 µm, 120 Å, 3 x 250 mm, 1/Pk - 07872-51 £415.00Buy Now

Nacalai Tesque COSMOSIL HILIC Analytical HPLC Column, 5 µm, 120 Å, 3 x 50 mm, 1/Pk - 04800-71

Cosmosil® HILIC Nacalai Tesque COSMOSIL HILIC Analytical HPLC Column, 5µm, 120Å, 3mm I.D. x 50mm Length, 1/Pk Product Number: 04800-71 HPLC Column for Hydrophilic Interaction Hydrophilic interaction chromatography is a variation of normal...
Nacalai Tesque COSMOSIL HILIC Analytical HPLC Column, 5 µm, 120 Å, 3 x 50 mm, 1/Pk - 04800-71
Live chat below or contact us for latest price.
... more info