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Nacalai Tesque COSMOSIL 3C18-MS-II Analytical HPLC Column, 3 µm, 120 Å, 4.6 x 75 mm, 1/Pk - 08758-31

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COSMOSIL C18-MS-II

Nacalai Tesque COSMOSIL 3C18-MS-II Analytical HPLC Column, 3µm, 120Å, 4.6mm I.D. x 75mm Length, 1/Pk

Product Number: 08758-31

COSMOSIL C18-MS-II is a monomeric type of C18 phase. A new endcapping treatment with polar groups for "shield effect" has extended the pH range and significantly improved peak shape for basic compounds. This phase is recommended for most of applications but particularly effective for low molecular weight organic compounds.

COSMOSIL Standard Reversed Phase Columns
Packing Material3C18-EBC18-MS-IIC18-AR-IIC18-PAQ
USP CodeL1
Silica GelHigh Purity Porous Spherical Silica
Average Particle Size3 µm3, 5, 15 µm
Average Pore Sizeapprox. 120 Å
Surface Areaapprox. 300 m2/g
Stationary PhaseOctadecyl Group
Bonding TypeMonomericPolymeric
Main InteractionHydrophobic Interaction
End Capping TreatmentNear-perfect Treatment
Carbon Contentapprox. 14.5%approx. 16%approx. 17%approx. 11%
pH Range2-10*1.5-7.5*2 - 7.5

Features: 

  • 3C18-EB - This phase with a better end-capping treatment offers improved peak shape and separation particularly for basic compounds.
  • C18-MS-II - This phase is recommended for most applications but particularly effective for basic compounds.
  • C18-AR-II - This phase is recommended for separations requiring acidic mobile phase conditions. It also shows superior molecular shape selectivity to monomeric type C18columns.
  • C18-PAQ - This phase is designed to offer superior retention of polar compounds and excellent reproducibility in highly aqueous mobile phases, even in 100% aqueous.

Available in the Following Configurations:

  • 2.5C18-MS-Ⅱ - 2.5 µm Particle Size
  • 3C18-MS-Ⅱ - 3 µm Particle Size
  • 5C18-MS-Ⅱ - 5 µm Particle Size
  • 15C18-MS-Ⅱ - 15 µm Particle Size

Specifications:

Product DescriptionCOSMOSIL 3C18-MS-II Packed Column (4.6 mm l.D. x 75 mm)
Number / Quantity1 pc
ManufacturerNacalai Tesque
Brand nameCosmosil
Product typeHPLC Column
length75 mm
inner diameter4.6 mm
Particle size3 µm
modificationC18 (RP-18, ODS, Octadecyl)
Modification (manufacturer)C18-MS-II
Silica gelHigh purity porous spherical silica
Bonding typeMonomeric type
Pore size120 Å
USP ClassL1
Carbon content16.0%
Specific surface area [m2/g]300.0
EndcappingEndcapped Waters Type
End capping treatmentNear-perfect treatment
Column typeAnalytical Column
Hardware materialstainless steel
Hardware TypeReady-to-use column
pH minimum2.0
pH maximum10.0
Separation technologyReversed Phase Chromatography (RP)
technologyHigh-Performance Liquid Chromatography (HPLC)
matrixSilica
Particle morphologyspherical, fully porous

Additional Column Sizes are available - Please contact our Sales Team with your requirements.

Cosmosil Columns Online Catalogue:


  • Model: 08758-31
  • Manufactured by: Nacalai Tesque