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COSMOSIL nNap Columns

Specialty for Structural Isomers / π-π interaction, excellent selectivity for unsaturated compounds

Separation of unsaturated compounds on conventional reversed phase columns such as C8 and C18 is often problematic. Phenyl stationary phases are commonly used for these compounds because they form π-π interactions and show different selectivity from conventional alkyl phases. However, the π-π interactions on phenyl stationary phases are moderate, and the separation for some unsaturated compounds are still insufficient.

COSMOSIL πNAP is a Reversed Phase HPLC Column with naphtylethyl group bonded silica packing material. The naphthylethyl group is composed of two fused aromatic rings and forms strong π-π interactions with unsaturated compounds. This column offers improved selectivity for structural isomers that exhibit differences in saturation.

COSMOSIL πNAP
USP codeL-11
Silica gelHigh purity porous spherical silica
Average particle size2.5 µm3 µm5 µm
Average pore sizeapprox. 130 Åapprox. 120 Åapprox. 120Å
Specific surface areaapprox. 330m2/gapprox. 300 m²/gapprox. 300 m²/g
Stationary phaseNaphtylethyl group
Bonding typeMonomeric
Carbon contentapprox. 11%-approx. 11%
Usable pH range2 - 7.5

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