Waters GTxResolve Premier BEH Amide FIT Column, 300 Å, 1.7 µm, 2.1 x 150 mm, 1/pk - 186011254

Waters GTxResolve Premier BEH Amide FIT Column, 300 Å, 1.7 µm, 2.1 x 150 mm, 1/pk

Part Number: 186011254

The GTx Resolve BEH Amide 1.7 µm, 2.1 x 150 mm Columns are designed for the analysis of oligonucleotides, nucleic acids, and viral protein capsids. Each batch of GTxResolve BEH Amide 300Å is quality control tested with the Waters Glycoprotein Performance Test Standard (P/N: 186008010) and Waters ssDNA 20 to 100 Ladder (P/N: 186009446). The column hardware incorporates MaxPeak High Performance Surface (HPS) that reduces unwanted analyte surface interactions and greatly improves peak shape, recovery, and reproducibility.

GTxResolve Premier BEH Amide Columns

High resolution, MS-compatible analysis for a wide range of GTx applications

Hydrophilic interaction chromatography (HILIC) is widely used for the retention and analysis of polar analytes, allowing analysts to separate up to 100 residue long single and double stranded oligonucleotides.

Accelerate the analysis of your polar analytes with Waters GTxResolve Premier BEH Amide methods that offer drug developers a platform approach for multiple analytes, and provide a valuable alternative to ion-pairing reversed-phase (IP-RP) methods that require dedicated LC and LC-MS systems.

• GTxResolve Premier Amide columns are double batch-tested to ensure optimal chromatographic performance for cell and gene therapeutics.
• Robust amide-bonded stationary phase provides numerous separation possibilities for an extensive range of nucleic acids and viral proteins.
• Reduce the need for lengthy column conditioning using low adsorption column hardware for improved recovery.
• Eliminate dependency on running separations with ion-pairing dedicated LC-MS systems.

VanGuard™ FIT (Fully Integrated Technology) Columns

A Practical and Reliable Solution for HPLC Column Protection

In some applications HPLC columns can be subject to particulate material or strongly adsorbing substances becoming trapped in the column, leading to increased column pressure and degraded performance. The most reliable solution to this problem is to use a guard column to prevent particulates and strongly adsorbing substances from reaching the analytical column. A guard column is designed to be replaced periodically, thereby restoring the performance of the separation. Using a guard column addresses the problem of column fouling but has a potential downside of reduced column efficiency and increased peak tailing due to added extra-column dispersion. The VanGuard FIT Column design minimizes extra-column dispersion, enabling users to take advantage of the benefits of guard columns, without sacrificing separation performance.

Benefits

• Minimal extra-column dispersion for a VanGuard FIT Column versus traditional guard configurations
• Risk of leaks reduced since there are no additional connections to make
• More consistent connections yield more consistent results

Related Products:

• 186009448 - ssDNA 20 to 100 Ladder
• 186001287 - Atlantis dC18 Column, 100Å, 3 µm, 2.1 mm X 30 mm, 1/pk
• 176004434 - QuanRecovery with MaxPeak HPS Vial Package (186009186) with pre-slit PTFE silicone cap and septum, 100/pk
• 186009705 - IonHance Ammonium Acetate pH 6.8 Concentrate
• 186010598 - siRNA LC-MS Standard

Specifications: