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Waters XSelect HSS C18 Columns

XSelect HSS C18 is a general purpose, high performance C18 chemistry with exceptional retention and peak shape for all compounds. Packed in ultra-low dispersion hardware, 2.5 µm eXtended Performance [XP] columns enable exceptional separation performance, robustness and throughput for HPLC assays while enabling a seamless transition path toward UPLC adoption.

Achieve unmatched reproducibility with a wide range of selectivity

Quickly and easily develop robust methods compatible with all modern chromatographic detection modes and transfer them from lab to lab with the XSelect Column family.

Designed to help you achieve reproducible and highly selective chromatographic separations, the XSelect Column family features two base particles technologies, Charged Surface Hybrid (CSH) and High Strength Silica (HSS). With XSelect Columns, method development scientists like you can achieve a wide range of selectivities across all application areas, without compromising performance.

  • Designed for selectivity and stability at low pH
  • Superior peak shape for basic compounds
  • Highest analyte mass loading available
  • Excellent batch-to-batch reproducibility
  • Ideal for rapid method development
  • Recommended Use: For improving selectivity, peak shape, and retentivity in methods development.

CSH Column chemistries: C18, Fluoro-Phenyl (PFP), and Phenyl-Hexyl, available in 2.5 XP, 3.5, 5 μm analytical and 10 μm OBD preparative sizes

HSS Column chemistries: HSS C18, C18 SB, and T3, available in 2.5 XP, 3.5, and 5 μm particle sizes
Prolonged column lifetimes with optional VanGuard Cartridges specifically designed using XSelect stationary phases



Item Name Product Image Price

Waters XSelect HSS C18 Guard Column, 100 Å, 5 µm, 19 mm x 10 mm, 1K-15K, 1/pk - 186011260

Waters XSelect HSS C18 Guard Column, 100Å, 5 µm, 19 mm x 10 mm, 1K-15K, 1/pk Part Number: 186011260 The HSS C18 is a general-purpose C18 bonded phase packed in this guard column that provides superior peak shape for bases, increased retention...
Waters XSelect HSS C18 Guard Column, 100 Å, 5 µm, 19 mm x 10 mm, 1K-15K, 1/pk - 186011260 £437.00
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Waters XSelect HSS C18 Guard Column, 100 Å, 5 µm, 30 mm x 10 mm, 1K-15K, 1/pk - 186011055

Waters XSelect HSS C18 Guard Column, 100Å, 5 µm, 30 mm x 10 mm, 1K-15K, 1/pk Part Number: 186011055 The HSS C18 is a general-purpose C18 bonded phase packed in this guard column that provides superior peak shape for bases, increased retention...
Waters XSelect HSS C18 Guard Column, 100 Å, 5 µm, 30 mm x 10 mm, 1K-15K, 1/pk - 186011055 £776.00
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Waters XSelect HSS C18 OBD Prep Column, 100 Å, 5 µm, 19 mm x 100 mm, 1/pk - 186011052

Waters XSelect HSS C18 OBD Prep Column, 100Å, 5 µm, 19 mm x 100 mm, 1/pk Part Number: 186011052 The HSS C18 is a general-purpose C18 bonded phase column that provides superior peak shape for bases, increased retention (vs. XBridge C18 columns),...
Waters XSelect HSS C18 OBD Prep Column, 100 Å, 5 µm, 19 mm x 100 mm, 1/pk - 186011052 £2,868.00
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Waters XSelect HSS C18 OBD Prep Column, 100 Å, 5 µm, 19 mm x 150 mm, 1/pk - 186011053

Waters XSelect HSS C18 OBD Prep Column, 100Å, 5 µm, 19 mm x 150 mm, 1/pk Part Number: 186011053 The HSS C18 is a general-purpose C18 bonded phase column that provides superior peak shape for bases, increased retention (vs. XBridge C18 columns),...
Waters XSelect HSS C18 OBD Prep Column, 100 Å, 5 µm, 19 mm x 150 mm, 1/pk - 186011053 £3,466.00
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Waters XSelect HSS C18 OBD Prep Column, 100 Å, 5 µm, 19 mm x 250 mm, 1/pk - 186011054

Waters XSelect HSS C18 OBD Prep Column, 100Å, 5 µm, 19 mm x 250 mm, 1/pk Part Number: 186011054 The HSS C18 is a general-purpose C18 bonded phase column that provides superior peak shape for bases, increased retention (vs. XBridge C18 columns),...
Waters XSelect HSS C18 OBD Prep Column, 100 Å, 5 µm, 19 mm x 250 mm, 1/pk - 186011054 £4,443.00
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Waters XSelect HSS C18 OBD Prep Column, 100 Å, 5 µm, 30 mm x 150 mm, 1/pk - 186011058

Waters XSelect HSS C18 OBD Prep Column, 100Å, 5 µm, 30 mm x 150 mm, 1/pk Part Number: 186011058 The HSS C18 is a general-purpose C18 bonded phase column that provides superior peak shape for bases, increased retention (vs. XBridge C18 columns),...
Waters XSelect HSS C18 OBD Prep Column, 100 Å, 5 µm, 30 mm x 150 mm, 1/pk - 186011058 £9,041.00
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Waters XSelect HSS C18 Sentry Guard Cartridge, 100 Å, 3.5 µm, 3 mm X 20 mm, 2/pkg - 186004764

Waters XSelect HSS C18 Sentry Guard Cartridge, 100 Å, 3.5 µm, 3 mm X 20 mm, 2/pkg Part Number: 186004764 The HSS C18 is a general-purpose C18 bonded phase column that provides superior peak shape for bases, increased retention (vs. XBridge C18...
Waters XSelect HSS C18 Sentry Guard Cartridge, 100 Å, 3.5 µm, 3 mm X 20 mm, 2/pkg - 186004764
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