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Waters XSelect Premier CSH Columns

XSelect Premier Columns

Maximize selectivity with problem-solving technologies for a wide range of analytes
Get the best injection to injection reproducibility in your chromatographic separations with Waters XSelect Premier 2.5 µm and 3.5 µm Columns, which utilize MaxPeak High Performance Surfaces (HPS) Technology. Ideal for the wide range of analytes encountered in method development, XSelect Premier Columns combine modern particle technologies and ligands with the protection of MaxPeak HPS Technology.

Designed to maximize selectivity, XSelect Premier Columns are built on one of two innovative base particle technologies, Charged Surface Hybrid (CSH) and High Strength Silica (HSS). The integration of MaxPeak HPS allows you to recover more and achieve balanced, controlled interactions between your analytes, mobile phase, and the column for the highest performance chromatographic separations.

Particle Stability with MaxPeak HPS Protection

Working at the extremes of temperature and pH while maximizing analyte peak shape is a significant challenge for methods development scientists. Now, with XBridge Premier 2.5 µm and 3.5 µm Columns, it doesn’t have to be.

XBridge Premier Columns prevent undesired analyte/surface interactions through the power of MaxPeak HPS Technology, which is designed to increase analyte recovery, sensitivity, and reproducibility by minimizing analyte/surface interactions that can lead to sample losses.

XBridge Premier Columns are the evolution of Waters XBridge XP (eXtended Performance) columns and XBridge HPLC columns, and they combine the industry-leading column stability of Ethylene Bridged Hybrid (BEH) particles with MaxPeak High Performance Surfaces (HPS) Technology.

CSH (Charged Surface Hybrid) Technology

The Charged Surface Hybrid (CSH) particle is Waters third generation hybrid particle technology. Based on Waters Ethylene Bridged Hybrid (BEH) particle technology, CSH particles incorporate a low-level surface charge that improves sample loadability and peak asymmetry in low-ionic-strength mobile phases, while maintaining the mechanical and chemical stability inherent in the BEH particle technology.

The advantages of CSH columns include:

  • Superior peak shape for basic compounds
  • Increased loading capacity
  • Rapid column equilibration after changing mobile-phase pH
  • Improved batch-to-batch reproducibility
  • Exceptional stability at low and high pH
  • Seamless transfer between HPLC and UPLC technology platforms
  • Available Particle Sizes: 1.7, 2.5, 3.5, 5, and 10 µm
  • Column Chemistries: C18, Phenyl-Hexyl, Fluoro-Phenyl

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