XSelect Premier Columns
Maximize selectivity with problem-solving technologies for a wide range of analytes
Get the best injection to injection reproducibility in your chromatographic separations with Waters XSelect Premier 2.5 µm and 3.5 µm Columns, which utilize MaxPeak High Performance Surfaces (HPS) Technology. Ideal for the wide range of analytes encountered in method development, XSelect Premier Columns combine modern particle technologies and ligands with the protection of MaxPeak HPS Technology.
Designed to maximize selectivity, XSelect Premier Columns are built on one of two innovative base particle technologies, Charged Surface Hybrid (CSH) and High Strength Silica (HSS). The integration of MaxPeak HPS allows you to recover more and achieve balanced, controlled interactions between your analytes, mobile phase, and the column for the highest performance chromatographic separations.
Particle Stability with MaxPeak HPS Protection
Working at the extremes of temperature and pH while maximizing analyte peak shape is a significant challenge for methods development scientists. Now, with XBridge Premier 2.5 µm and 3.5 µm Columns, it doesn’t have to be.
XBridge Premier Columns prevent undesired analyte/surface interactions through the power of MaxPeak HPS Technology, which is designed to increase analyte recovery, sensitivity, and reproducibility by minimizing analyte/surface interactions that can lead to sample losses.
XBridge Premier Columns are the evolution of Waters XBridge XP (eXtended Performance) columns and XBridge HPLC columns, and they combine the industry-leading column stability of Ethylene Bridged Hybrid (BEH) particles with MaxPeak High Performance Surfaces (HPS) Technology.
HSS (High Strength Silica) Technology
High pore volume HPLC particles do not possess the mechanical stability necessary to withstand the high pressures inherent in UPLC separations. Waters material scientists addressed this challenge by developing a silica particle designed for high mechanical stability with the appropriate morphology to provide long UPLC column lifetimes and high UPLC efficiencies at high pressures. The 1.8 µm High Strength Silica (HSS) particle is the first and only 100% silica particle designed, tested, and intended for use in applications up to 15,000 psi (1034 bar).
The advantages of HSS columns include:
- High retentivity for polar organic compounds and metabolites
- Balanced retention of polar and hydrophobic analytes
- Mechanical stability at high pressures
- Seamless transfer between HPLC and UPLC technology platforms
- Available Particle Sizes: 1.8, 2.5, 3.5, and 5 µm
- Column Chemistries: C18, C18SB, T3, PFP, CN
