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Waters ACQUITY UPLC Evaporative Light Scattering (ELS) Detector

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ACQUITY UPLC Evaporative Light Scattering (ELS) Detector

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See more of what you need and see it faster

Increase peak confidence across a wide application range with optimal UPLC/ELS (ELSD) performance in a small footprint. The ACQUITY UPLC Evaporative Light Scattering (ELS) Detector from Waters offers unparalleled performance when monitoring compounds with poor to no ultraviolet/visible response and analytes that do not ionize well in mass spectrometry.

This detector has been designed specifically for ACQUITY UPLC PLUS series systems and engineered for a variety of sample sizes—particularly for high volume or open access environments and anywhere large numbers of compounds are screened rapidly. The ACQUITY UPLC ELS Detector offers a convenient stackable design, easy maintenance, and long lamp lifetimes.

Overview

  • Achieve enhanced compatibility with a variety of detection techniques, providing a more comprehensive UPLC-MS analysis, and ensuring confidence that all components in the sample have been detected
  • Attain precise control over nebulization and desolvation processes for reproducible and reliable measurement of temperature-sensitive samples
  • Achieve simplified set-up and maximized performance over the entire flow rate ranges of ACQUITY UPLC PLUS series systems with the single nebulizer
  • Attain easy maintenance and maximum up-time with the pre-aligned snap-in lamp
  • Improve peak definition and confidence in quantitative results with data rates up to 80 Hz
  • Send a "Stop Flow" signal to LC pump when low gas pressure is detected

Recommended Use: Add a new dimension of performance and system versatility to analyses where compounds have poor to no UV/Vis response.

See more information per run

The ACQUITY UPLC ELS Detector enables users to see more information per chromatographic run. Evaporative light scattering technology allows the monitoring of compounds that do not have a UV/Vis response and do not ionize well in mass spectrometry. This innovative detector can, therefore, efficiently supplement other detectors.

Ginko Biloba Ethyl Acetate Extract: Dual detection mode results using an ACQUITY UPLC System together with ACQUITY TUV and ELS Detectors. 1) Bilobalide 2) Ginkgolide J 3)  Ginkgolide C 4) Ginkgolide A and 5) Ginkgolide B.

Ginko Biloba Ethyl Acetate Extract: Dual detection mode results using an ACQUITY UPLC System together with ACQUITY TUV and ELS Detectors. 1) Bilobalide 2) Ginkgolide J 3) Ginkgolide C 4) Ginkgolide A and 5) Ginkgolide B.

Achieve ultimate flexibility with multiple detector options

A suite of detectors for samples where some of the components lack chromophores or do not ionize well by mass spectrometry is key to the success of your laboratory.

The ACQUITY UPLC ELS Detector has precise temperature control for the nebulization and desolvation process to cover the entire ACQUITY UPLC PLUS series flow rate range, conveniently allowing you to run samples under different conditions. The detector also provides a snap-in self-aligning lamp and nebulizer for easy serviceability. 

Triple detection of a mixture of pharmaceuticals highlights the value of each detector in this separation.

Triple detection of a mixture of pharmaceuticals highlights the value of each detector in this separation.

Resolution, sensitivity, and speed designed to suit your needs

Monitoring product batches and carrying quality control of finished goods is intrinsic in pharmaceutical and chemical analysis laboratories. The ACQUITY UPLC PLUS series line of products is critical for the resolution, sensitivity, and speed required in such environments.

ACQUITY UPLC ELS Detector trace for the analysis of three eye drop formulations.

ACQUITY UPLC ELS Detector trace for the analysis of three eye drop formulations.

Specifications:

Nebulizer Front mounted, snap-in design
Temperature control nebulizer chamber Heater 0 to 100%, thermally controlled, cooler on/off
Gas Nitrogen, to be supplied, at least 65 psi
Temperature range drift tube 0.1 °C increments, feedback accuracy to 0.1 °C
Eluent flow rate maximum 100% water at 2 mL/min
Filter setting Hamming, 0 to 5.0 seconds in 0.1 second increments
Optics Heated optics bench (constant 50 °C)
Light source Tungsten halogen polychromatic, front mounted, pre-aligned, user installable
Detector Photomultiplier tube
Voltage range 0 to 1250 VDC
Range 0.1 to 2000 light scattering units full scale
Physical specifications Width: 34.3 cm (13.5 inches)
Height: 21.6 cm (8.5 inches)
Depth: 51.8 cm (20.4 inches)

 


  • Model: ACQUITY UPLC ELS Detector
  • Manufactured by: Waters