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QLA Transdermal Patch Holder, 120 Mesh Screen, 2.20” (56mm) Opening - APPFIVE-V56 (12-4230)

Price: £64.04


Qty. 
+-
Transdermal Patch Holder, 120 Mesh Screen for USP App 5
2.20 inches
 
(56mm) Opening. 
Use in Paddle Over Disk Applications
Pack Contents: Each
Equivalent to Varian VanKel OEM No: 12-4230


Method
Transdermal or patch testing is carried out using USP method 5 (paddle over disc) or USP method 6, the rotating cylinder. 
With paddle over disc, the transdermal patch is placed between a glass disc and an inert PTFE mesh. This is placed at the bottom of the vessel, with the mesh facing upwards, under a rotating paddle. 
Unlike dissolution testing, transdermal testing is carried out at 32°C to reflect the lower temperature of the skin. Other variables such as the height setting and sampling requirements are the same as dissolution testing.

The APPFIVE-HR watch glass patch holder is a borosilicate 
watch glass with a 17 mesh PTFE screen, held together 
by plastic clips. Patches up to 90mm in diameter can be 
tested. It is compatible with all brands of dissolution bath 
and conforms exactly to the USP specification.

With paddle over disc, a transdermal patch is placed either 
between a glass disc and an inert PTFE mesh (APPFIVE-HR), 
or directly onto a stainless steel mesh (APPFIVE-V35, 
APPFIVE-V56 and APPFIVE-V80). This is placed at the 
bottom of the vessel, with the mesh facing upwards, under 
a rotating paddle.

Transdermal testing is carried out at 32°C to reflect the 
temperature of the skin. 
Other variables such as the height setting and sampling 
requirements are the same as for USP Method 2.

The USP 5 apparatus is compatible with all brands of 
dissolution bath.

  • Model: APPFIVE-V56
  • Manufactured by: QLA

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