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Biomiga Tumor Red - TR-01

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Description :

Description:

TumorRed is a nanoparticle fluorescent in vivo blood vessel leakage imaging agent. TumorRed enables imaging of circulation,blood vessels, vasculature, vascular leak, including that associated with various stage s of oncologic and opthalmologic lesions.

Material

Contents

TumorRed: Each vial contains 500 µL TumorRed at a concentration of 2 µG/µL, in 1xPBS. The TumorRed solution has been filtered through a 0.2 µm filter. This material provides sufficient reagent for imaging approximately 5 mice (weighing ~20-25 grams each) when using the recommended dose of 200 µG of TumorRed per mouse.

Table 1. TumorRed Characteristics

Property

Specification

Particle

~100 nm

Fluorescence1

• Excitation

• Emission

620 ± 5 nm

670 ± 5 nm

Absorbance1

620 ± 5 nm

Purity2

>95%

Appearance

Dark blue suspension

1. Absorbance and fluorescence maxima of TomorRed in 1x PBS.

2. As determined by RP-HPLC and measuring absorbance at 620 nm.

Storage and Handling

  • Upon receipt, TumorRed should be IMMEDIATELY STORED AT 4 oC AND PROTECTED FROM LIGHT.
  • When stored and handled properly, TumorRed is stable for up to six months.
  • Allow TumorRed imaging agent doses to equilibrate to room temperature before injecting into animals.

 

In Vivo Imaging and Applications

  • The generally recommended procedure for in vivo imaging with TumorRed is administration via tail vein injection and imaging 12 - 72 hours post injection.
  • TumorRed enables imaging of various types of solid tumors  specifically at 24-72 hours poster injection. It also enables imaging of circulation, blood vessels, vasculature and vascular leak.

Imaging equipment

  • In vivo imaging: any fluorescent in vivo imager
  • Ex vivo imaging: any fluorescent dissecting microscope
  In vivo imaging of human cancer subcutaneous xenograft tumor
with TumorRed. (24 hours post vein injection)
  Absorbance and fluorescence emission spectra of TumorRed.

Notes

Biomiga's TumorRed is intended for research purposes only and is not for human use. It must be used by or directly under the supervision of a technically qualified individual experienced in handling potentially hazardous materials. Please read the Material Safety Data Sheet (MSDS) provided for this product.

Several of Biomiga's products and product applications are covered by U.S and foreign patents and patents pending. Our products are not available for resale or other commercial uses with out a specific agreement from Biomiga.

 


 


  • Model: TR-01
  • Manufactured by: Biomiga

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