Imtakt 2mm ID, 5mm Length, Guard cartridge for 2-4.6mmI.D. columns (30MPa) 3pcs/pk - GCDX0S

DACAPO DX-C18 Porous Silica / Organic Polymer Dual-Matrix ODS

Dacapo DX-C18 2.5μm 5mm x 2.0mm Guard Cartridge, Pack of 3

Imtakt Product Number GCDX0S

Column Specifications:

Dacapo DX-C18 is one of the most innovative columns that we have created. This 2.5µm particle is manufactured by Imtakt and uses our Dual-Matrix Technology, which is a monumental advancement in column design. Other columns boast surface treatments that extend pH stability, but there isn’t anything else out there like Dacapo. All of our columns use a polymeric end-capping, which is already a step above other so-called high pH columns, but with Dacapo, we have taken that concept to the extreme. In addition to our polymeric end-capping, Dual-Matrix Technology then adds several polymer layers on top of that, making this the best high pH C18 available today.

• Imtakt's first column featuring Dual-Matrix Technology
• Most complete surface coverage of any high pH column on the market
• 2.5µm particle provides superior efficiency
• Extreme polymer surface treatment provides a wide pH range from 1-12
• UHPLC-compatible
• Ideal for basic compounds
• Simple eluent for LC-MS using ammonium hydroxide
• ESI-negative mode for peptides
• Alkali sample solution / Alkali column washing

The advantage of using traditional silica-based particles is that they have a high mechanical strength; their disadvantage is that they are prone to degradation under alkali conditions. On the other hand, polymer-based particles are highly resistant to degradation under alkali conditions, but they suffer from poor performance and durability due to shrink/swelling effects when used with organic solvents. One recent solution to this dilemma is the porous hybrid-silica with alkyl bridge surface treatment. This requires exposure of surface silanols in order to bond the ODS ligands by silylation, which is then followed by an end-capping process. Even when care is taken in this strategy, it is difficult to completely cover all remaining surface silanols, which may negatively affect peak shape and reduce lifetime of the column due to bleeding under alkali conditions.

Wide pH-range Simple alkali eluents for LC-MS analysis
The base structure of the DACAPO material is an innovative chromatography support which consists of both mechanical and alkali stable structures. It is designed specifically for the analysis of peptides, alkaloids, and other compounds under alkali conditions using simple volatile eluents like ammonium hydroxide. This design is also quite useful for the use of high pH sample solutions for injection and/or alkali column washing conditions. The "Dual Matrix" design also provides benefit under acidic conditions, which might be preferable to improve peak shape of basic compounds, by nearly eliminating any silanol effect.

Range of Presto FF-C18 Columns, 2µm Non-Porous Silica, Octadecyl Ligand, End-Capped, Product Numbers:

Dacapo DX-C18 Guard System

All stationary phases can also be made in the following internal diameters, please contact our Sales Team with your specificatons: Nano: 0.02mm, 0075mm | Capillary: 0.1mm, 0.3mm, 0.5mm | Semi-Prep: 20mm, 28mm

Additional Imtakt Columns Available

• Imtakt Scherzo
• Imtakt Intrada
• Imtakt Cadenza
• Imtakt Presto
• Imtakt Unison
• Imtakt DACAPO
• Imtakt Guard