Cosmosil® PYE - Pyrenylethyl
Nacalai Tesque COSMOSIL 5PYE Pyrenylethyl Semi-preparative HPLC Column, 5µm, 120Å, 20mm I.D. x 150mm Length, 1/Pk
Product Number: 05948-31
Reversed phase HPLC columns have been widely used because of their superior resolution, high theoretical plate number and ease of use. Since hydrophobic interaction is the dominant separation mechanism in reversed phase chromatography, conventional stationary phases such as C18 and C18 do not offer optimum selectivity for compounds with similar hydrophobicity. COSMOSIL offers a broad selection of columns with unique stationary phases for separation of these difficult analytes. These columns offer improved separation of structurally similar compounds that are difficult to analyse with a C18 type column.
COSMOSIL PYE (Pyrenylethyl group bonded) and COSMOSIL NPE (Nitrophenylethyl group bonded) column show unique retention characteristics based on multiple separation modes such as hydrophobic, charge transfer and π-π interactions. These columns are recommended for the separation of structural isomers.
COSMOSIL PYE column is a reversed phase column with 2-(1-Pyrenyl) ethyl groups bonded silica packing material. This column utilizes π-π interactions originating from the planar pyrene ring structure to separate structural isomers.
- Pyrenylethyl group bonded stationary phase
- Separation with high molecular shape selectivity or π-π interactions
- Excellent separation for structural isomers
COSMOSIL PYE | COSMOSIL NPE | |
Silica Gel | High Purity Porous Spherical Silica | |
Average Particle Size | 3PYE - 3 μm 5PYE - 5 μm | 5 μm |
Average Pore Size | approx. 120 Å | |
Stationary Phase | 2-(1-Pyrenyl)ethyl Group | Nitrophenylethyl Group |
Main Interaction | Hydrophobic Interaction π-π Interaction Charge Transfer Interaction Stereoselectivity | Hydrophobic Interaction π-π Interaction Dipole-Dipole Interaction |
Carbon Content | approx. 18% | approx. 9% |
Column Specifications:
Product description | Cosmosil® 5PYE Packed Column 20mmx150mm |
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Quantity | 1 pc |
Manufacturer | Nacalai Tesque |
Brand | Cosmosil |
Product Type | HPLC Column |
Length | 150 mm |
Internal Diameter | 20 mm |
Particle Size | 5 µm |
Chemistry Producers Term | PYE (Pyrenylethyl) |
Pore Size | 120 Å |
Carbon Load | 18.0 % |
Bet Surface Area [m2/g] | 300.0 |
Endcapping | End-Fitting: Waters type |
Column Type | Semi-preparative Column |
Hardware Material | Stainless Steel |
Hardware Type | Ready-to-use Column |
pH Minimum | 2.0 |
pH Maximum | 7.5 |
Mode of Separation | Reversed Phase Chromatography (RP) |
Technology | High-Performance Liquid Chromatography (HPLC) |
Matrix | Silica |
Particle Morphology | spherical, fully porous |
Additional Column Sizes are available - Please contact our Sales Team with your requirements.
Cosmosil Columns Online Catalogue:
- Model: 05948-31
- Manufactured by: Nacalai Tesque