Nacalai Tesque COSMOSIL CHiRAL 5C Cellulose tris (5-dichlorophenyl carbamate) Semi-preparative Column, 5 µm, 20 x 250 mm, 1/Pk - 15792-51

COSMOSIL® CHiRAL Series

Nacalai Tesque COSMOSIL CHiRAL 5C Cellulose tris (5-dichlorophenyl carbamate) Packed Semi-preparative Column, 5μm, 20mm I.D. x 250mm Length, 1/Pk

Product Number: 15792-51

Immobilized Polysaccharide Derivative-Based Chiral Columns

The COSMOSIL CHiRAL series uses a chiral selector that is chemically bonded to the silica gel, which results in high resistance to solvents. Tetrahydrofuran (THF) strips coated selectors from the stationary phase, reducing theoretical plates to less than 1/5 in our experiment. However, the same selectors bonded to the silica withstood repeated injections of THF.

COSMOSIL CHiRAL columns are available in 3 µm particles, which yield sharper peaks than conventional 5 µm particles. Columns for preparative separations are available with 5 µm particles.

Features:

• Immobilized selectors can withstand many different solvents
• Sharpen peaks with 3 µm particles
• Preparative separations with 5 µm particles
• Equivalent performance to columns currently on the market Competitive price

The COSMOSIL CHIRAL 3 series (3 µm particles) puts moderately higher pressure on the system compared to conventional 5 µm particles. This improves reproducibility for low-pressure solvents, such as hexane, that may otherwise cause pump irregularities. At the lowest concentration of 5% (v/v), the backpressure was 5.3 MPa. This range allows high flexibility in mobile phase composition and selectivity.

COSMOSIL Chiral columns are compatible with SFC and exhibit similar performance compared to HPLC.

COSMOSIL CHiRAL offers 3 different chiral selectors that, together, have a high probability of separating your sample. Of 28 samples in our test, 27 pairs of enantiomers were fully separated. For samples that do not separate easily with any column, please adjust the type and concentration of solvents in your mobile phase.

Chiral Series Consists of the Following :

• Type A = Amylose tris (3,5-dimethylphenyl carbamate)
• Type B = Cellulose tris (3,5-dimethylphenyl carbamate)
• Type C = Cellulose tris (3,5-dichlorophenyl carbamate)

Available in the Following Particle Sizes:

• CHiRAL 3A / 3B / 3C - 3 μm Particle Size
• CHiRAL 5A / 5B / 5C - 5 μm Particle Size

Specifications:

Additional Column Sizes are available - Please contact our Sales Team with your requirements.

Cosmosil Columns Online Catalogue:

• Nacalai Tesque COSMOSIL HPLC Columns
• Nacalai Tesque COSMOCORE UHPLC Columns
• Nacalai Tesque Reagents, Standards, Solvents