Waters XBridge BEH Phenyl OBD Prep Column, 130 Å, 5 µm, 50 mm x 150 mm, 1/pk - 186011261

Waters XBridge BEH Phenyl 5µm OBD Prep Column, 130 Å, 5 µm, 50 mm x 150 mm, 1/pk

Part Number: 186011261

XBridge BEH Phenyl columns provide complementary selectivity to C18 stationary phases, especially for polyaromatic compounds. This is the most chemically stable commercially available Phenyl sorbent on the market and provides you with ultra-low column bleed, long column lifetimes and excellent peak shape.

Preparative HPLC Columns

Increase throughput with preparative productivity and predictability of small molecules, proteins, peptides, and nucleic acid-based analytes.
As a scientist working on the research, development and commercialization of diagnostic or therapeutic drugs it can be challenging to create methods that are robust, scalable and provide high yield and purity across various preparative LC platforms.

As your lab works to achieve fast, efficient, lab-scale separations and greater throughput, Waters Preparative HPLC Columns can help you attain predictable performance and easily scale from UPLC, UHPLC, or HPLC screening to lab-scale purification. With the proprietary Optimum Bed Density (OBD) design of Waters Preparative HPLC Columns, you can ensure consistency in column-to-column performance and increase productivity through higher recoveries and longer column lifetimes – making lost samples, repeat purification runs, and poor scalability from small to large volume columns a thing of the past.

Select XBridge and XSelect OBD Preparative Columns are now available in MaxPeak HPS Technology hardware in 2.5, 3.5, and 5 µm particle sizes. MaxPeak Premier OBD Preparative Columns prevent undesired compound/surface interactions, leading to poor peak shapes/purities, low sensitivity, and target sample loss.

• Achieve fast, efficient, lab-scale separations for greater throughput
• Directly scale from analytical UPLC, UHPLC, or HPLC screening to lab-scale purification
• Select robust chromatographic particles designed for purification
• Increase productivity through higher recoveries and longer column lifetimes

XBridge OBD Preparative Columns

• High pH and temperature stability
• Increased mass loading for basic compounds
• Increased column lifetime with OBD technology
• Direct scalability from analytical to prep
• Benefits of BEH particle technology
• Pore sizes: 130 Å and 300 Å
• Particle sizes: 2.5 µm, 3.5 µm, 5 µm, and 10 µm
• Application-specific chemistries for: proteins, peptides, and oligonucleotides
• Simplifies method transfer between laboratories
• QC-tested for peptide, protein and oligonucleotide applications
• Available with MaxPeak Premier HPS Technology

BEH (Ethylene Bridged Hybrid) Technology

Ethylene Bridged Hybrid (BEH) particle technology ensures maximum column performance and longer column lifetimes under all chromatographic conditions. The hybrid particle technology offers many advantages over conventional silica-based particles, including the ability to control silanol activity for better reproducibility, peak shape, and efficiency. The BEH particle is created from two high purity monomers: tetraethoxysilane (TEOS) and bis(triethoxysilyl) ethane (BTEE), which results in highly stable, pH resistant, and mechanically strong particles that set the performance standard for method development. BEH particle technology allows for seamless transfer from analytical to preparative separations.

The advantages of BEH columns include:

• Rugged hybrid organic/inorganic base particle
• Improved peak shape for bases-low silanol activity
• Wider operating pH range for method development flexibly
• Mechanical strength for maximum column efficiency at UHPLC operating pressures
• Available Particle Sizes: 1.7, 2.5, 3.5, 5, and 10 µm
• Column Chemistries: C18, C18 AX, Shield RP18, C8, Phenyl, Amide, Z-HILIC, HILIC

Related Products:

• 186006703 - Preparative Chromatography Mix Standard
• 186006031 - XBridge BEH C18 Column, 130Å, 2.5 µm, 2.1 mm X 100 mm, 1/pk
• 186003116 - XBridge BEH C18 Column, 130Å, 5 µm, 4.6 mm X 150 mm, 1/pk

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