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Waters ACQUITY UPLC and ACQUITY Premier PDA eLambda Detectors

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ACQUITY UPLC and ACQUITY Premier PDA eLambda eλ Detectors

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PDA detection for spectral exposure optimizationACQUITY Premier PDA e? Detector

Getting accurate and complete spectral information to make better decisions about your analysis can be a challenge. The ACQUITY UPLC and ACQUITY Premier Photodiode Array (PDA) eλ Detectors enable a laboratory to detect and quantify lower concentrations of sample analytes as well as compare spectra across the ultraviolet and visible wavelengths, allowing analyses encompassing a broader concentration range. 

The detectors meet multiple UPLC-MS detection strategy requirements and provide the ability to map low levels of compounds and determine trace impurity levels within a compound’s peak.

Overview

  • Quantitate trace impurities with high optical and digital resolution
  • Library matching and peak purity assessment for increased confidence in compound identification
  • Data rates of up to 80 Hz, noise specifications of ±3 µAU, and reproducible integration allows for detection of peaks generated by fast UPLC/PDA separations
  • Efficient light transmission and low noise characteristics for maximum sensitivity
  • Simultaneous 2D and 3D operation in either Empower or MassLynx Software
  • Lamp intensity optimized by unique software to maintain minimal noise levels across the entire deuterium spectrum for the life of the lamp

Recommended Use: Detect and quantify lower concentrations of sample analytes and compare spectra across a broad wavelength range.

Unmatched sensitivity with enhanced flexibility

The Waters ACQUITY UPLC and ACQUITY Premier PDA eλ Detectors are specifically designed to complement Performance UHPLC/UPLC Systems. These detectors have data rates up to 80 Hz, noise specifications of ±3 μAU, and sensitivity that is unmatched by any other photodiode array detector on the market. Further, enhanced software control provides flexibility for simultaneous 2D and 3D operations in Empower or MassLynx software.

Sensitivity improvements up to 4X are observed using spectral exposure optimization. For three FD&C dyes, sensitivity improvements ranged from 1.4 to 1.9 with the ACQUITY UPLC PDA e? Detector.

Sensitivity improvements up to 4X are observed using spectral exposure optimization. For three FD&C dyes, sensitivity improvements ranged from 1.4 to 1.9 with the ACQUITY UPLC PDA eλ Detector.

Optimal performance across the entire spectrum range

The expanded wavelength range of the ACQUITY UPLC and ACQUITY Premier PDA eλ Detectors provides for highly sensitive spectral information in the visible region. Noise performance in lower energy regions of the deuterium spectrum is improved while maintaining optimal performance across the entire range.

UPLC separation of extracted ball point pen ink components in 30 seconds at 600 nm with the ACQUITY UPLC PDA e? Detector.

UPLC separation of extracted ball point pen ink components in 30 seconds at 600 nm with the ACQUITY UPLC PDA eλ Detector.

Specifications:

Wavelength range 190 to 800 nm
Wavelength accuracy ±1 nm
Linearity range Deviation at 2.0 AU ≤5%, propylparaben, at 257 nm
Optical resolution 1.2 nm
Digital resolution 1.2 nm/pixel
Baseline noise ±3 μAU, 230 nm, 2 Hz, 2 s, wavelength compensation 310 to 410, WET (2D channel)
Drift ≤1.0 x 10-3/AU/hour/°C
Sampling rate Up to 80 points/s
Light source Prealigned, intelligent technology Deuterium lamp
Dispersion volume ≤0.8 μL (Analytical flow cell); ≤1.5 μL (High sensitivity flow cell)
Flow cell design Light-guiding UPLC intelligent technology flow cell
Path length 10 mm (analytical flow cell)
Flow cell volume 500 nL (analytical flow cell)
Wetted materials 316 stainless-steel, fused silica, Teflon™ polytetrafluoroethylene (PTFE) AF, PEEK (analytical flow cell)
Pressure limit 1000 psi (all flow cells)
Flow cell options
  • Analytical: 500 nL, 10 mm path length
  • High sensitivity: 2400 nL, 25 mm path length
  • High throughput: 135 nL, 3 mm path length
  • Stainless-steel: 1500 nL, 5 mm path length
  • Titanium: 1500 nL, 5 mm path length
  • ACQUITY Premier PDA Flow Cell, HPS
  • Titanium: 5 mm, AP
Physical specifications
  • Width: 34.3 cm (13.5 inches)
  • Height: 19.4 cm (7.6 inches)
  • Depth: 60.7 cm (23.9 inches)

 


  • Model: ACQUITY UPLC/Premier PDA eLambda
  • Manufactured by: Waters