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Waters 2545 Binary Gradient Module Pump - 186025450

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2545 Binary Gradient Module (BGM)

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Purification Solvent Management

Flexible and scalable modular pumps

As your lab’s productivity demands increase, so do your expectations for reliability, performance, and flexibility of your solvent delivery system. 

Waters innovative preparative pump technologies provide extraordinary performance and convenience for benchtop purification of microgram to multigram sample loads. The full range of Binary and Quaternary Gradient Modules have been designed to meet all your purification needs.

Overview

  • Easily configurable modules for a variety of purification protocols covering a wide range of sample matrices 
  • Exceptional flow rates provide you with the precision and accuracy you require 
  • Chromatographic reproducibility that you need to fully automate all your laboratory’s processes 
  • Exceptional solvent blending, automated solvent management, and pulse-free delivery, to meet even your most sensitive application challenges

Recommended Use: For flexible solvent delivery, whether for isocratic or gradient, or analytical or preparative.

2545 Binary Gradient Module

The Waters® 2545 Binary Gradient Module (BGM) is a high-pressure mixing binary gradient pump that serves as the primary solvent delivery device for the Waters AutoPurification™ System. The 2545 BGM provides consistently smooth, pulse-free solvent flow for both analytical- and preparative-scale flow rates under MassLynx™ Software control with the FractionLynx™ Application Manager.

The 2545 Binary Gradient Module (BGM) is a high-pressure mixing binary gradient pump that serves as the primary solvent delivery device for the LC Prep AutoPurification System, enabling subsequent isolation and purification of targeted compounds.

Features:

  • Operates at analytical and preparative scales
  • Performs between flow rates of 0.50 to 150.00 mL/min with a pressure up to 6000 psi
  • Integrates solvent selection valves on each solvent delivery channel to allow for rapid solvent changeovers and system purges
  • Streamlines the purification process via MassLynx Software control using FractionLynx Application Manager
OPERATING SPECIFICATIONS
Flow rate range 0.50 to 150.00 mL/min
Primary wetted materials 316 stainless steel, UHMWPE, Sapphire, Ruby, Tefzel® (ETFE), Teflon® (FEP, PTFE, PFA), Nitronic 60, Valcon H, Chemraz, and PEEK
Flow rate increment 0.01 mL/min
Delay volume 350 μL maximum
Flow accuracy ±1.0% of required flow or 10 μL/min, whichever is greater (MeOH or water at 600 psi)
Composition accuracy ±1.0% absolute (full scale) from 5 to 95% from 1 to 130 mL/min (MeOH or water step gradients)
Composition precision Retention time variation <0.3% RSD or 0.1 min SD, whichever is greater
(Dial-a-mix, uracil/caffeine, 6 replicates, 1, 20, 50 mL/min, 70/30 water/MeOH)
Gradient composition curves Eleven (11) gradient curves including linear, step [2], concave [4], and convex [4]
Priming Self prime from solvent container on floor with dry lines
Number of solvents Up to four: A1 or A2 and B1 or B2
Pump seal
Pump seal wash Integral, active, programmable
Maximum operating pressure 6,000 psi up to 100 mL/min; Rolloff to 5,000 psi at 150 mL/min
Leak Test Fully automatic diagnostic
INSTRUMENT CONTROL AND COMMUNICATION
Number of contact closure outputs Four (4)
Stop flow input TTL signal or contact closure
Start gradient input TTL signal or contact closure
Auxiliary input Two (2) TTL signal or contact closure (One (1) dedicated to leak detector)
Chart outputs Two (2) 0 to 2 volts per scale
Ethernet RJ45 connector
PHYSICAL/ ENVIRONMENTAL SPECIFICATIONS
Dimensions Width: 28.2 cm (11.1 in.)
Height: 42.7 cm (16.8 in.) 
Depth (no drip tray): 63.5 cm (25.0 in.)
Weight: 57.0 kg (125.0 lbs.)
Operating temperature 4 to 40? C
Operating humidity 20 to 80%, non-condensing
Acoustic noise < 60 dBA at idle
ELECTRICAL SPECIFICATIONS
Power requirements 6.5 A
Line voltage 100 to 240 Vac ±10%
Frequency 50/60 Hz
Fuse 10 A, 5 x 20 mm, slow-blow, IEC type
Power consumption 650 W
ORDERING INFORMATION
2545 Binary Gradient Module 186025450

 


  • Model: 186025450
  • Manufactured by: Waters