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Waters 2545 QGM Quaternary Gradient Module Prep Pump - 176001736

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2545 QGM Quaternary Gradient Module Prep

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Purification Solvent Management

Flexible and scalable modular pumps

As your lab’s productivity demands increase, so do your expectations for reliability, performance, and flexibility of your solvent delivery system. 

Waters innovative preparative pump technologies provide extraordinary performance and convenience for benchtop purification of microgram to multigram sample loads. The full range of Binary and Quaternary Gradient Modules have been designed to meet all your purification needs.

Overview

  • Easily configurable modules for a variety of purification protocols covering a wide range of sample matrices 
  • Exceptional flow rates provide you with the precision and accuracy you require 
  • Chromatographic reproducibility that you need to fully automate all your laboratory’s processes 
  • Exceptional solvent blending, automated solvent management, and pulse-free delivery, to meet even your most sensitive application challenges

Recommended Use: For flexible solvent delivery, whether for isocratic or gradient, or analytical or preparative.

2535, 2545, and 2555 Quaternary Gradient Modules

The 2535, 2545, and 2555 Quaternary Gradient Modules (QGMs) are four solvent, low-pressure mixing gradient pumps that serve as solvent delivery devices for purification systems. Dual programmable flow paths enable the system volumes to change when the column size is changed.

2535 QGM 50 mL/min capability for using columns up to 30 mm I.D. for purification of milligrams of material
High pressure operation at 6,000 psi (414 bar) to accommodate a wide variety of column lengths, diameters, and particle sizes
2545 QGM 150 mL/min capability for using columns up to 50 mm I.D. for purification of milligrams to grams of material
High pressure operation at 6,000 psi (414 bar) up to 100 mL/min with a roll off to 5,000 psi (345 bar) at 150 mL/min to accommodate a wide variety of column lengths, diameters, and particle sizes
2555 QGM
2555 QGM 300 mL/min capability for using columns up to 75 mm I.D. for grams of material
High pressure operation of 3000 psi (207 bar) at 200 mL/min with a roll off to 2,500 psi (172 bar) at 300 mL/min to accommodate a wide variety of column lengths, diameters, and particle sizes

 

QGM Features:

  • Four-solvent gradient selection
  • Two fluidic pathways (small scale and large scale) to accommodate column selection and chromatographic efficiency
  • Control from MassLynx or Empower software or console, allowing scale up via a familiar software interface
  • Interfaces to a variety of detectors and peak fraction collectors for optimum purifications
  • Allows UV- or MS-directed purification with MassLynx Software
  • Leak detection is standard

2545 QGM

The Waters® 2545 Quaternary Gradient Module (QGM) is a low-pressure mixing quaternary gradient pump (for flow-rates up to 150 mL/min) that serves as a solvent delivery device for purification systems.

  • 150 mL/min capability for using columns up to 50 mm I.D. for purification of milligrams to grams of material
  • High pressure operation at 6,000 psi (414 bar) up to 100 mL/min with a roll off to 5,000 psi (345 bar) at 150 mL/min to accommodate a wide variety of column lengths, diameters, and particle sizes
OPERATING SPECIFICATIONS
Number of solvents Up to four: A, B, C, D
Solvent conditioning Sparging: one channel per solvent
Flow-rate range 0.50 to 150.00 mL/min, in 0.01 mL/min increments
Compressibility compensation Automatic and continuous
Delay volume < 6.5 mL
Plunger seal wash Integral, active, programmable
Gradient profiles 11 gradient curves, including linear, step [2], concave [4], and convex [4]
Priming Self prime from solvent container on floor with dry lines
Maximum operating pressure 6000 psi up to 100 mL/min; Roll off to 5000 psi at 150 mL/min ±
Composition accuracy 3% absolute (full scale) from 5% to 95%; and from
1 to 150 mL/min (methanol or water step gradients) at 600 psi
Composition precision Retention time variation < 0.15 min SD,
(uracil/caffeine; 1, 5, 20, 50, 150 mL/min; 70:30 water/methanol dial-a-mix)
Primary wetted materials 316 stainless steel, Ultra-high-molecular-weight polyethylene UHMW PE blend, sapphire, ruby, Tefzel™ ETFE (ethylene-tetrafluoroethylene), Teflon™ (fluorinated ethylene propylene FEP, Polytetrafluoroethylene PTFE, Perfluoroalkoxy alkanes PFA), Valcon H, Nitronic 60, and Polyether ether ketone PEEK
Flow accuracy ± 1.0% of required flow (methanol or water at 600 psi)
Leak test Fully automatic diagnostic
INSTRUMENT CONTROL AND COMMUNICATION
Number of contact closure outputs Four (4)
Stop flow input TTL signal or contact closure
Start gradient input TTL signal or contact closure
Auxiliary input two TTL signal or contact closure (one dedicated to leak detector)
Chart outputs Two 0 to 2 volts per scale
Ethernet RJ45 connector
PHYSICAL/ENVIRONMENTAL SPECIFICATIONS
Dimensions Width: 28.0 cm (11.0 in.)
Height: 43.2 cm (17.0 in.)
Depth (no drip tray): 66.0 cm (26.0 in.)
Weight 39.5 kg (87.0 lbs.)
Operating temperature 4.0 to 40.0 °C (39.2 to 104.0 °F)
Operating humidity 10% to 90%, non-condensing
Acoustic noise < 60 dBA
ELECTRICAL SPECIFICATIONS
Power requirements 6.5 A
Line voltage 100 to 240 Vac ± 10%
Frequency 50/60 Hz
Fuse 10 A, 5 x 20 mm, slow-blow, IEC type
Power consumption 650 W
ORDERING INFORMATION
Description Part number
2545 Quaternary Gradient Module Prep 176001736
Chromatography Rack (Optional) 205000619
FlexInject (Optional) 205000237

 

 


  • Model: 176001736
  • Manufactured by: Waters

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