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Waters LC Prep 150 System

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LC Prep 150 System

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A versatile system to suit your purification requirements 

The LC Prep 150 System is a fit-for-purpose solution designed for scientists requiring robust system performance with intuitive software for dedicated personal purification or quick adoption in centralized labs.

Ideal for workflows where rapid separations of complex mixtures are required, this versatile system is designed to satisfy your application requirements, whether you are processing a few samples a day, or your workload demands greater throughput with unattended automation. With the LC Prep 150 System, your lab can rapidly process your valuable complex mixtures—resulting in high purity and recovery with complete confidence.

  • Ideally suited for initial workflow criteria requiring rapid preparative separations of complex mixtures
  • Robust system performance with intuitive ChromScope Software
  • Rapidly process your complex mixtures with complete confidence

Recommended Use: Ideal for dedicated personal purification or quick adoption in centralized labs with robust system performance and intuitive software.

Purification, made simple

The Waters LC Prep 150 System and ChromScope Software make purification simple. Meet your laboratory’s purification needs with the LC Prep 150 System, including options like:

  • Flexible solvent delivery options, including binary or quaternary based pumps for low-pressure multi-solvent blending or high-pressure gradient mixing of flow rates up to 150 ml/min
  • Easy to use manual or automated sample injection options for the versatility to accommodate a wide range of workload requirements
  • Highly sensitive detectors, enabling you to identify and isolate compounds of interest with enhanced linear range to accommodate highly concentrated samples
  • A reliable easy-to-use fraction collector for highly precise sample collection, with flexible collection racks and vessel options accommodating a variety of fraction sizes
  • Easy-to-navigate ChromScope Software, delivered with sample set wizard, stacked injection wizard, key fraction collection parameters, fraction simulation modeling, and customizable reporting with drop and drag features.
  • Internal column diameters of up to 50 mm, to confidently purify sample loads of milligrams to grams 

Robust ChromScope Software featuring collection method development allows you to simulate and optimize your fraction collection parameters without using valuable sample.

Robust ChromScope Software featuring collection method development allows you to simulate and optimize your fraction collection parameters without using valuable sample.

Specifications:

Preparative System Specifications*
Operating flow rate range Programmable from 0 to 150 mL/min, in 0.01 increments
Operating pressure range 5000 psi (345 bar)
Supported column dimensions 10, 19, 30, and 50 mm I.D.
Wetted material 316 stainless steel, UHMWPE, sapphire, ruby, Tefzel (ETFE), Teflon (FEP, PTFE, FPA), nitronic 60, vlacon H, chemraz, and PEEK
Software ChromScope
*Individual component specifications may allow operation outside the total system defined parameters. The system is designed and tested only for the ranges defined in system specifications. 
Solvent Management
  2545 Binary System 2545 Quaternary System
Dwell volume ≤350 μL <6.5 mL
Flow accuracy ±1.0% of required flow or10 μL/min, whichever is greater(MeOH or water at 600 psi) ±1.0% of required flow (MeOH or water at 600 psi)
Composition accuracy ±1.0% of required flow or5% to 95%, and from 1 to 150 mL(MeOH or water step gradients) ±3% absolute (full scale) from 5% to 95%, and from 1 to 150 mL/min (MeOH or water step gradients) at 600 psi
Composition precision Retention time variation <0.3% RSD or 0.1 min SD, whichever is greater (dial-a-mix, uracil/caffeine, 6 replicates, 1, 20, 50 mL/min, 70:30 water/MeOH) Retention time variation <0.15 min SD, (dial-a-mix uracil/caffeine; 1, 5, 20, 50, 150 mL/min; 70:30 water/MeOH)
Number of solvents Up to four: A1 or A2, B1 or B2 Up to four selectable. 0% to 100% programmable in .01% increments for each reservoir
Gradient composition curves Eleven (11) gradient curves including linear (1), step (2), concave (4), and convex (4)
Compressibility compensation Automatic and continuous
Pump seal wash Integral, active, programmable
Priming Self-prime from solvent container on floor with dry lines
WFC III
Collection capacity
  • Standard test tube (13.0 to 18.0 mm) rack (120 tubes)
  • Eppendorf tube rack (120 tubes)
  • Scintillation vial (16.5 mm) rack (120 vials)
  • Scintillation vial (27.5 mm) rack (56 vials)
  • Microtiter plate rack (4 x 96/384)
  • Preparative funnel rack (4 x 32 positions)
  • Multipurpose rack
Prep Injector Module
Injector 3725i continuous flow design (MBB)
Flex Injector Module
Injectors
  • 7725i analytical continuous flow design (MMB)
  • 3725i continuous flow design (MMB)
2707 Sample Manager
Injection volume 0 to 10,000 μL in 1 μL increments
Sample loop volume 10 mL sample loop
Sample capacity Two 12-vial trays for 10 mL vials
Syringe size 2.5 mL
Power Requirements
Voltage 100 to 240 VAC
Frequency 50 to 60 Hz
Physical Dimensions
Manual
  • Width: 71 cm (28 inches)
  • Height: 64 cm (25 inches)
  • Depth: 64 cm (25 inches)
Prep 150Q LC w/TUV Weight: 60 kg (132 pounds)
Prep 150B LC w/TUV Weight: 78 kg (171 pounds)
Prep 150Q LC w/PDA Weight: 63 kg (140 pounds)
Prep 150B LC w/PDA Weight: 80 kg (177 pounds)
Automated
  • Width: 86 cm (34 inches)
  • Height: 64 cm (25 inches)
  • Depth: 64 cm (25 inches)
Prep 150Q LC w/TUV Weight: 75 kg (165 pounds)
Prep 150B LC w/TUV Weight: 93 kg (205 pounds)
Prep 150Q LC w/PDA Weight: 78 kg (172 pounds)
Prep 150B LC w/PDA Weight: 95 kg (209 pounds)

 


  • Model: LC Prep 150 System
  • Manufactured by: Waters

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