Imtakt Cadenza CD-C18 MF 2mm ID, 250mm Length, 3um,ODS,end-capped, Metal-Free Column - CD026F

Cadenza CD-C18 Metal-Free ODS Column, optimized for Steric Selectivity

Cadenza CD-C18 3µm 2.0mm x 250mm (ODS end-capped) HPLC Analytical Metal-Free Column, Pressure Limits of up to : 50MPa, 500 bar, 7,500 psi

Imtakt Product Number CD026F

Download the Metal-Free Column Brochure

Column Specifications:

The Cadenza family of columns is a high-quality series of ODS columns with a ligand density optimized for steric selectivity. These powerful columns are able to distinguish subtle differences in your analytes making it an excellent choice for isomer separation, or detection of impurities. These columns have low back pressure due to the high quality of materials used in their manufacturing. With a unique polymeric end-capping these columns will also provide very little unwanted secondary interactions and better peak shape.

• Unique ligand density provides excellent steric selectivity
• High efficiency 3µ ODS column with low back-pressure
• Excellent for impurity testing or isomer separation
• Selectivity ideal for small molecule pharmaceutical testing or drugs of abuse
• HT and UP hardware able to operate in pressures up to 1000 bar
• Better separation of Hydrophobic Compounds
• Higher steric selectivity
• High plate count at a low flow rate

This column is a leader in high throughput. Cadenza yields equal or better results, but with a shorter column length. This results in three major benefits:
1.    Shorter analysis time
2.    Less solvent use
3.    More efficient methods development

Cadenza CD-C18 demonstrates impressive plate numbers and exceptionally high recognition of molecules in the stationary phase. The 250 x 4.6 mm columns, in particular can provide 50,000 plates per column.

Achieve Higher Efficiencies with Shorter Cadenza CD-C18 Columns

The shorter Cadenza CD-C18 75 mm x 4.6 mm can replace your conventional 150 mm x 4.6 mm and provides:

• Similar or improved resolution
• Half the analysis time
• Improved concentration and sensitivity
• Half the conditioning time
• Half the solvent use

It is also easy to switch conditions for gradient analysis. Gradient time is reduced by 50%, which the gradient's initial and final concentration remains the same. In the case of Isocratic analysis, the same conditions apply. Cadenza offers improved sensitivity with the same resolution by fully realizing the power of a 3µm particle column design.

Cadenza offers an advantage of 13,000 plates in a 75mm column, double that of a same dimension 5µm ODS column, therefore achieving the same separation quality as a conventional column with a shorted Cadenza column.

For the highest throughput, use the shortest column that gives you sufficient separation and resolution. Cadenza CD-C18 comes in unusually short sizes of 10mm, 20mm and 30mm, allowing the minimum run times. 

Cadenza CD-C18 Metal-free HPLC Columns

Improving peak shape for chelating or phosphoric compounds

2 mm I.D. - 30-250 mm Length - PEEK / SS316 - UHPLC compatible

• Metal-free (PEEK) internal structuren 
• UHPLC compatible metal housing
• Ideal for chelating compounds
• Ideal for phosphoric compounds
• LC-MS compatible 2mm I.D.
• Wide selection of stationary phases

This metal-free column is an Imtakt original design. The entire internal surface of these columns are made with PEEK material, including the frits, and is therefore extremely inert with respect to chelating compounds. The outer portion of these columns are made from stainless steel (SS316) making them suitable for extremely high pressures, and are UHPLC compatible. 

Phosphoric compounds can interact with the exposed metal surfaces within the column causing peak tailing, as seen in the figure to the left.

Imtakt's metal-free columns are designed to specifically improve these poor peak shapes by decreasing unwanted secondary chelating effects.

Improving peak shape of chelating or phosphoric compounds
Chelating and phosphoric compounds often have difficulty with poor peak shape and/or sensitivity due to undesired interaction between metal parts in the column and the structure of these compounds. Imtakt's UHPLC compatible metal-free columns, which are an Imtakt original design, will improve these
problems and are available in a wide range of stationary phases.

Range of Cadenza CD-C18 3µm Columns, Product Numbers:

Column Guard System for Cadenza CD-C18:

All stationary phases can also be made in the following internal diameters, please contact our Sales Team with your specificatons: Nano: 0.02mm, 0075mm | Capillary: 0.1mm, 0.3mm, 0.5mm | Semi-Prep: 20mm, 28mm

This column is also available in particle size 5µm!

• Imtakt Cadenza 5CD-C18 5µm

Additional Imtakt Columns Available

• Imtakt Scherzo
• Imtakt Intrada
• Imtakt Cadenza
• Imtakt Presto
• Imtakt Unison
• Imtakt DACAPO
• Imtakt Guard