Cadenza CL-C18 Silanol-regulated C18
Cadenza CL-C18 MF 3µm 30mm x 2mm, 120Å (ODS controlled endcapping) Metal-Free Analytical Column, Pressure limits of up to : 20MPa, 250 bar, 3,000 psi
Imtakt Product Number CL021F
Column Specifications:
Base Material: | Silica |
Quantity: | 1 piece |
Chemistry: | C18 (RP-18, ODS, Octadecyl) |
Manufacturer Chemistry Name: | CL-C18 |
Endcapping: | controlled endcapping |
Matrix: | Silica |
Brand: | Imtakt Cadenza |
Internal Diameter: | 2 mm |
Length: | 30 mm |
Particle Morphology: | spherical, porous |
Particle Size: | 3 µm |
Pressure Stability: | up to 250 bar |
Pore Size: | 120 Å |
Technology: | HPLC Metal-Free |
USP Class: | L1 |
World’s First Silanol Regulated ODS Phase
The Cadenza family of columns is a high quality series of ODS columns with a ligand density optimized for steric selectivity. These powerful columns are able to distinguish subtle differences in your analytes making it an excellent choice for isomer separation, or detection of impurities. These columns have low back pressure due to the high quality of materials used in their manufacturing. With a unique polymeric end-capping these columns will also provide very little unwanted secondary interactions and better peak shape.
- Unique ligand density provides excellent steric selectivity
- World’s first silanol-regulated ODS phase provides additional selectivity options for ionic compounds
- High efficiency 3µ ODS column with low back-pressure
- HT and UP hardware able to operate in pressures up to 1000 bar
Due to its partial endcapping, the Cadenza CL-C18 opens a new world of separation possibilities. Almost all recent ODS columns have complete endcapping. However, complete endcapping makes some separations impossible. Conversely, ODS columns without any endcapping provide poor elution characteristics due to the influence of silanol. Our new Cadenza CL-C18 with partial encapping uniquely optimizes the remaining silanol. The difference between Cadenza CL-C18 and CD-C18 is that CL-C18 has more silanol remaining on the material surface. An example of the retention activity for an ionized compound (imazalil, pKa=ca.6) is pictured (above left) and shows the influence on eluent separation and retention of CL-C18’s remaining silanol. Imazalil retention is greatest with columns that are not endcapped, followed by CL-C18, and CD-C18, in that order.
Cadenza CL-C18 Metal-free HPLC Columns
Improving peak shape for chelating or phosphoric compounds
2 mm I.D. - 30-250 mm Length - PEEK / SS316 - UHPLC compatible
- Metal-free (PEEK) internal structuren
- UHPLC compatible metal housing
- Ideal for chelating compounds
- Ideal for phosphoric compounds
- LC-MS compatible 2mm I.D.
- Wide selection of stationary phases
This metal-free column is an Imtakt original design. The entire internal surface of these columns are made with PEEK material, including the frits, and is therefore extremely inert with respect to chelating compounds. The outer portion of these columns are made from stainless steel (SS316) making them suitable for extremely high pressures, and are UHPLC compatible.
Phosphoric compounds can interact with the exposed metal surfaces within the column causing peak tailing, as seen in the figure to the left.
Imtakt's metal-free columns are designed to specifically improve these poor peak shapes by decreasing unwanted secondary chelating effects.
Improving peak shape of chelating or phosphoric compounds
Chelating and phosphoric compounds often have difficulty with poor peak shape and/or sensitivity due to undesired interaction between metal parts in the column and the structure of these compounds. Imtakt's UHPLC compatible metal-free columns, which are an Imtakt original design, will improve these
problems and are available in a wide range of stationary phases.
Range of Cadenza CL-C18 Columns, Product Numbers:
Column Length (mm) | Analytical | Semi-prep | |||||
1.0 mm I.D. | 1.5 mm I.D. | 2.0 mm I.D. | 3.0 mm I.D. | 4.6 mm I.D. | 6.0 mm I.D. | 10.0 mm I.D. | |
3µm Columns, Pressure limits of up to: 20MPa, 250 bar, 3,000 psi | |||||||
10 | CL020 | CL030 | CL000 | ||||
20 | CL029 | CL039 | CL009 | ||||
30 | CL011 | CL071 | CL021 | CL031 | CL001 | CL061 | CL0P1 |
50 | CL012 | CL072 | CL022 | CL032 | CL002 | CL062 | CL0P2 |
75 | CL013 | CL073 | CL023 | CL033 | CL003 | CL063 | CL0P3 |
100 | CL014 | CL074 | CL024 | CL034 | CL004 | CL064 | CL0P4 |
150 | CL015 | CL075 | CL025 | CL035 | CL005 | CL065 | CL0P5 |
250 | CL016 | CL076 | CL026 | CL036 | CL006 | CL066 | CL0P6 |
500 | CL007 | ||||||
3µm Columns, Pressure limits of up to: 50MPa, 500 bar, 7,500 psi | |||||||
10 | CL020T | CL030T | CL000T | ||||
20 | CL029T | CL039T | CL009T | ||||
30 | CL011T | CL071T | CL021T | CL031T | CL001T | ||
50 | CL012T | CL072T | CL022T | CL032T | CL002T | ||
75 | CL013T | CL073T | CL023T | CL033T | CL003T | ||
100 | CL014T | CL074T | CL024T | CL034T | CL004T | ||
150 | CL015T | CL075T | CL025T | CL035T | CL005T | ||
250 | CL016T | CL076T | CL026T | CL036T | CL006T | ||
3µm UHPLC (UP) Columns, Pressure limits of up to : 100MPa,1000 bar, 15,000 psi | |||||||
30 | CL021U | ||||||
50 | CL022U | ||||||
75 | CL023U | ||||||
100 | CL024U | ||||||
150 | CL025U | ||||||
250 | CL026U | ||||||
3µm Metal-Free Columns, Pressure limits of up to: 20MPa, 250 bar, 3,000 psi | |||||||
30 | CL021F | ||||||
50 | CL022F | ||||||
75 | CL023F | ||||||
100 | CL024F | ||||||
150 | CL025F | ||||||
250 | CL026F |
Column Guard System for Cadenza CL-C18
Product Number | Product Name | Description | |||||
GCCL0C | Guard Cartridge CL-C18 | 3um,ODS,Controlled end-Capping (5x1mm), 3pcs | |||||
GCCL0M | Guard Cartridge CL-C18 | 3um,ODS,Controlled end-Capping (10x8mm), 2pcs | |||||
GCCL0S | Guard Cartridge CL-C18 | 3um,ODS,Controlled end-Capping (5x2mm), 3pcs | |||||
GCH01S | Guard Holder | Guard Holder for 1-6mmI.D. separation columns | |||||
GCH02M | Guard Holder | Guard Holder for 10-20mmI.D. separation columns | |||||
GCH11S | Guard Holder | Guard Holder for 4.6mm column, enclosed an U-Shape column coupler | |||||
GCH12M | Guard Holder | Guard Holder for 10-20mm column, enclosed an U-Shape column coupler |
All stationary phases can also be made in the following internal diameters, please contact our Sales Team with your specificatons: Nano: 0.02mm, 0075mm | Capillary: 0.1mm, 0.3mm, 0.5mm | Semi-Prep: 20mm, 28mm
This Column is also available in 5 µm!
Additional Imtakt Columns Available
- Model: CL021F
- Manufactured by: Imtakt