Imtakt Cadenza CL-C18 MF 2mm ID, 50mm Length, 3um,ODS,Controlled end-Capping, Metal-Free Column - CL022F

Cadenza CL-C18 Silanol-regulated C18

Cadenza CL-C18 MF 3µm 50mm x 2mm, 120Å  (ODS controlled endcapping) Metal-Free Analytical Column, Pressure limits of up to : 20MPa, 250 bar, 3,000 psi

Imtakt Product Number CL022F

Column Specifications:

World’s First Silanol Regulated ODS Phase

The Cadenza family of columns is a high quality series of ODS columns with a ligand density optimized for steric selectivity. These powerful columns are able to distinguish subtle differences in your analytes making it an excellent choice for isomer separation, or detection of impurities. These columns have low back pressure due to the high quality of materials used in their manufacturing. With a unique polymeric end-capping these columns will also provide very little unwanted secondary interactions and better peak shape.

• Unique ligand density provides excellent steric selectivity
• World’s first silanol-regulated ODS phase provides additional selectivity options for ionic compounds
• High efficiency 3µ ODS column with low back-pressure
• HT and UP hardware able to operate in pressures up to 1000 bar

Due to its partial endcapping, the Cadenza CL-C18 opens a new world of separation possibilities. Almost all recent ODS columns have complete endcapping. However, complete endcapping makes some separations impossible. Conversely, ODS columns without any endcapping provide poor elution characteristics due to the influence of silanol. Our new Cadenza CL-C18 with partial encapping uniquely optimizes the remaining silanol. The difference between Cadenza CL-C18 and CD-C18 is that CL-C18 has more silanol remaining on the material surface. An example of the retention activity for an ionized compound (imazalil, pKa=ca.6) is pictured (above left) and shows the influence on eluent separation and retention of CL-C18’s remaining silanol. Imazalil retention is greatest with columns that are not endcapped, followed by CL-C18, and CD-C18, in that order.

Cadenza CL-C18 Metal-free HPLC Columns

Improving peak shape for chelating or phosphoric compounds

2 mm I.D. - 30-250 mm Length - PEEK / SS316 - UHPLC compatible

• Metal-free (PEEK) internal structuren 
• UHPLC compatible metal housing
• Ideal for chelating compounds
• Ideal for phosphoric compounds
• LC-MS compatible 2mm I.D.
• Wide selection of stationary phases

This metal-free column is an Imtakt original design. The entire internal surface of these columns are made with PEEK material, including the frits, and is therefore extremely inert with respect to chelating compounds. The outer portion of these columns are made from stainless steel (SS316) making them suitable for extremely high pressures, and are UHPLC compatible. 

Phosphoric compounds can interact with the exposed metal surfaces within the column causing peak tailing, as seen in the figure to the left.

Imtakt's metal-free columns are designed to specifically improve these poor peak shapes by decreasing unwanted secondary chelating effects.

Improving peak shape of chelating or phosphoric compounds
Chelating and phosphoric compounds often have difficulty with poor peak shape and/or sensitivity due to undesired interaction between metal parts in the column and the structure of these compounds. Imtakt's UHPLC compatible metal-free columns, which are an Imtakt original design, will improve these
problems and are available in a wide range of stationary phases.

Range of Cadenza CL-C18 Columns, Product Numbers:

Column Guard System for Cadenza CL-C18

All stationary phases can also be made in the following internal diameters, please contact our Sales Team with your specificatons: Nano: 0.02mm, 0075mm | Capillary: 0.1mm, 0.3mm, 0.5mm | Semi-Prep: 20mm, 28mm

This Column is also available in 5 µm!

• Imtakt Cadenza 5CL-C18

Additional Imtakt Columns Available

• Imtakt Scherzo
• Imtakt Intrada
• Imtakt Cadenza
• Imtakt Presto
• Imtakt Unison
• Imtakt DACAPO
• Imtakt Guard