Imtakt Scherzo SW-C18 MF 2mm ID, 100mm Length, 3um,multi-mode ODS (RP+Anion+Cation), Metal-Free Column - SW024F

Scherzo SW-C18 Metal-free multi-mode ODS HPLC Column

Scherzo SW-C18 Metal-free Reversed Phase (RP) + Anion Exchange (AX) + Cation Exchange (CX) Multi-Mode ODS Analytical HPLC Column

Imtakt Part Number: SW024F

Download the Scherzo C18 Series Brochure

Column Specifications

The world's first cation and anion IEX multimode ODS column. Low amount of strong ionic ligands, effective for strong ionic compounds.

• Simultaneous analysis of both cationic and anionic compounds
• Three kinds of packings with different ion exchange capacities
• For polar compounds
• Different selectivity from conventional ODS columns
• LC-MS compatible without using ion-pair reagents
• ODS column consists of C18+anion+cation ligand
• Purified Porous Silica / 3um Particle / 13nm Pore
• Polar and non-polar retention in Reversed Phase conditions
• Multi-level retention without ion-pairing reagents
• Compatible with LC-MS
• Most unique selectivity of any HPLC column on the market today
• Wide range of method development possibilities
• Can simultaneous optimize organic, buffer and pH gradients
• Low amount of strong ionic ligands, effective for strong ionic compounds

The Scherzo family of columns is one of the most unique and versatile series of columns on the market today. These multi-mode columns utilize reversed phase, cation and anion exchange, as well as normal phase modes all on the same column, virtually eliminating the need for ion-pairing reagents. Ideal for the simultaneous analysis of polar and non-polar analytes from vitamins, to metabolomics saving time and resources.

Multi-mode ODS Scherzo C18 columns consist of ODS ligands which have reversed-phase mode, plus anion and cation ligands which have anion/cation exchange modes. Three kinds of Scherzo columns have individual ion exchange capacities to find the best column for target compounds which have different ionic properties. Moreover, hydrophobicity between Scherzo C18 and Unison UK-C18, a conventional ODS, is similar, so these columns can be used as comparisons during method development.

Range of Scherzo SW-C18 Columns

Scherzo SW-C18 Metal-free HPLC Columns

Improving peak shape for chelating or phosphoric compounds

2 mm I.D. - 30-250 mm Length - PEEK / SS316 - UHPLC compatible

• Metal-free (PEEK) internal structuren 
• UHPLC compatible metal housing
• Ideal for chelating compounds
• Ideal for phosphoric compounds
• LC-MS compatible 2mm I.D.
• Wide selection of stationary phases

This metal-free column is an Imtakt original design. The entire internal surface of these columns are made with PEEK material, including the frits, and is therefore extremely inert with respect to chelating compounds. The outer portion of these columns are made from stainless steel (SS316) making them suitable for extremely high pressures, and are UHPLC compatible. 

Phosphoric compounds can interact with the exposed metal surfaces within the column causing peak tailing, as seen in the figure to the left.

Imtakt's metal-free columns are designed to specifically improve these poor peak shapes by decreasing unwanted secondary chelating effects.

Improving peak shape of chelating or phosphoric compounds
Chelating and phosphoric compounds often have difficulty with poor peak shape and/or sensitivity due to undesired interaction between metal parts in the column and the structure of these compounds. Imtakt's UHPLC compatible metal-free columns, which are an Imtakt original design, will improve these
problems and are available in a wide range of stationary phases.

Range of Scherzo SW-C18 Metal Free Columns

Other Imtakt Metal-free HPLC Columns

Additional Imtakt Columns Available

• Imtakt Scherzo
• Imtakt Intrada
• Imtakt Cadenza
• Imtakt Presto
• Imtakt Unison
• Imtakt DACAPO
• Imtakt Guard