COSMOSIL Quinoline group
Alternate selectivity to HP and PY
Supercritical Fluid Chromatography (SFC) has become more attractive because it offers some advantages over HPLC, such as high speed, unique selectivity and environmentally friendly separations. Many conventional normal-phase stationary phases, such as diol, amino and cyano, have been used for SFC applications. However, these phases present limitations for separations. COSMOSIL SFC Columns have been developed to enhance the capability of SFC separations.
The structural similarities between polar lipids, such as cholesterol and related analogs, have posed chromatographic and spectrometric challenges to analysts interested in quantifying these potential biomarkers. COSMOSIL Quinoline has been developed to improve the separation of these structural isomers utilizing the w-w interactions and structural rigidity of the naphthylethyl phase and the hydrogen bonding of the pyridine phase.