Waters Alliance HPLC High Throughput System

Alliance High Throughput HPLC Systems

Please contact our Sales Team for a quote.

Productivity. Precision. Reliability.

Waters offers the Alliance High Throughput (HT) HPLC System to help laboratories meet the demand of 24 x 7 operation. Built around the 2795 Separations Module, Alliance HT Systems optimize automated sample and solvent management to shave valuable seconds from each step of the chromatography process. The system is designed specifically to improve the productivity of labs that require the selectivity and sensitivity of LC/MS to produce quality data.

Today’s pharmaceutical laboratories are charged with moving thousands of samples through drug discovery screening processes, all while maximizing return on investment in both time and resources. You depend on automation to increase sample throughput and handle any sample format – tubes, vials, and/or well plates – all while meeting the need to produce reliable results and identify leads. Waters understands that when your lab is operating around the clock, keeping up with throughput demand means every second in your system’s analysis time counts.

The Waters® Alliance® HPLC High Throughput (HT) System with integrated and automated sample and solvent management is optimized for high efficiency separations, allowing valuable seconds to be saved from each step of the chromatography process. The Alliance HPLC HT System is specifically designed to improve the productivity of labs that require the selectivity and sensitivity of LC/MS to produce high quality data.

The Alliance HPLC HT System features:

• Flexible modes of LC operation (sequential and parallel)
• Sample format versatility – plates, tubes, or vials
• Automated SystemPREP routine for rapid unattended system equilibration
• Purge-wash-purge capability for minimal sample carryover
• Designed with Efficiency in Mind

From sample prep, analysis, sensitivity, and quantitation hurdles, to uptime, compliance maintenance, and support concerns, your Alliance HPLC HT System will allow you to meet these challenges and achieve the best performance and productivity for your laboratory’s requirements.

Choice of sample processing modes

Its integrated software and hardware design offers you the choice of traditional sequential mode or parallel processing. Parallel sample processing can reduce cycle time by performing multiple chromatographic and system operations simultaneously. While one sample is running, the next sample aspirates and loads; it is immediately injected once the previous sample run is complete. This accelerated injection-to-injection process greatly reduces cycle time, and allows more samples to be analyzed in less time.

Environmental control and sample stability

Controlling the environmental conditions of samples is accomplished with a Peltier-based heating and cooling module, which promotes sample stability, minimizes evaporation, and stabilizes labile samples. The factory-installed sample heater/ cooler option maintains temperatures from 4 to 40 °C.

Auto-process up to 1536 samples

The robotics-based three-axis (X, Y, Z) sample manager provides expanded sample capacity for processing up to 1536 samples configured in four plates. The instrument stores pre-programmed coordinates for standard microtiter plates, or lets you input custom coordinates. To prevent needle damage and allow for minimal sample volumes, a sensing routine determines the well or vial bottom. And with rapid, automated initialization, system start-up is quick and easy.

Dual solvent wash

The Alliance HPLC HT System utilizes two solvents to purge, wash, and re-purge the needle assembly, loop, and injection port. This reduces the risk of sample carryover and assures assay integrity – critical for ADME and metabolite research – making it ideal for high-sensitivity LC/MS/MS.

No tools are necessary

Primary components, such as seals and pistons, can be maintained by hand.

Robust solvent management

The solvent management system blends up to four chromatographic solvents in precise proportions for smooth, pulse-free solvent flow delivery. This ensures that over multiple runs, your results are precise time after time. The PerformancePLUS™ In-line Degasser efficiently removes gases from the chromatographic solvents. A fifth chamber in the degasser handles purge solvent used in the sample management system.

Automated valve switching

Change column methods, run multiple methods, or perform unattended methods development with automated valve switching, for up to three or six columns. Columns can be heated or cooled in a Peltier-based forced air recirculation oven.

Related Products:

Related Products:

• Waters 2489 UV/Visible (UV/Vis) Detector

• Waters Switching Valves