Cadenza 5CX-C18 Polar End-Capping ODS Column
Cadenza 5CX-C18 Polar End-Capping 150mm x 1.5mm, 5μm, 120Å, Analytical HPLC Column, Pressure limits of up to: 20MPa, 250 bar, 3,000 psi
Imtakt Product Number 5CX075
Column Specifications:
Base Material: | Silica |
Quantity: | 1 piece |
Chemistry: | C18 (RP-18, ODS, Octadecyl) |
Manufacturer Chemistry Name: | 5CX-C18 |
Endcapping: | Polar End Capping |
Matrix: | Silica |
Brand: | Imtakt Cadenza |
Internal Diameter: | 1.5 mm |
Length: | 150 mm |
Particle Morphology: | spherical, porous |
Particle Size: | 5 μm |
Pressure Stability: | up to 250 bar |
Pore Size: | 120 Å |
Technology: | HPLC |
pH: | 2-10 |
MW: | up to 10 kDa |
USP Class: | L1 |
High steric selectivity and molecular recognition C18 column for general use, ideal for separation of
isomers and other difficult to separate compounds. Polar end-capping technology provides a more complete coverage of surface silanols and unique selectivity.
Conventional ODS columns, including hybrid-silica type columns, require extensive end-capping in order to decrease residual silanols, which may negatively affect peak shape for basic compounds. Traditionally, this end-capping process has used methyl silane compounds which have a mild hydrophobic interaction. Viewing this interaction in terms of reversed-phase mode, the surface of the stationary phase presents two very different kinds of hydrophobic structures, octadecyl ligands (C18) and the methyl end-capping. These different hydrophobicities may provide an inconsistent response against a solutes interaction with the stationary phase, resulting in poor peak shape and reduced plate counts. Instead of relying on traditional end-capping with trimethyl silane (TMS) compounds, we have succeeded to develop a revolutionary surface modification technology using alcohol structures, which has been adapted to our brand new Cadenza CX-C18. This means that electrostatic interaction from the polar end-capped surface and hydrophobic interaction from the C18 ligand will localize the polarity of the surface and increase the recognition power of a complex compounds hydrophobic/hydrophilic structure. Therefore, Cadenza CX-C18 will have an alternative selectivity for certain compounds and possibly improved peak shape compared to conventional end-capped ODS columns.
- Imtakt's first column featuring modified alcohol polar end-capping
- Nearly 100% coverage of active surface silanol sites
- Reduces tailing for basic compounds in acidic conditions
- Alternative selectivity from traditional C18 columns
- High steric selectivity and molecular recognition
- Ideal for difficult isomer or impurity separations
Range of Cadenza 5CX-C18 Columns, Product Numbers:
Column Length (mm) | Analytical | Semi-prep | Prep | |||||||
1.0 mm I.D. | 1.5 mm I.D. | 2.0 mm I.D. | 3.0 mm I.D. | 4.0 mm I.D. | 4.6 mm I.D. | 6.0 mm I.D. | 10.0 mm I.D. | 20.0 mm I.D. | 28.0 mm I.D. | |
5µm Columns, Pressure limits of up to: 20MPa, 250 bar, 3,000 psi | ||||||||||
30 | 5CX011 | 5CX071 | 5CX021 | 5CX031 | 5CX001 | 5CX061 | 5CX0P1 | |||
50 | 5CX012 | 5CX072 | 5CX022 | 5CX032 | 5CX002 | 5CX062 | 5CX0P2 | 5CX0Q2 | ||
75 | 5CX013 | 5CX073 | 5CX023 | 5CX033 | 5CX003 | 5CX063 | 5CX0P3 | |||
100 | 5CX014 | 5CX074 | 5CX024 | 5CX034 | 5CX004 | 5CX064 | 5CX0P4 | 5CX0Q4 | ||
150 | 5CX015 | 5CX075 | 5CX025 | 5CX035 | 5CX045 | 5CX005 | 5CX065 | 5CX0P5 | 5CX0Q5 | |
250 | 5CX016 | 5CX076 | 5CX026 | 5CX036 | 5CX046 | 5CX006 | 5CX066 | 5CX0P6 | 5CX0Q6 | 5CX0R6 |
Column Guard System for Cadenza 5CX-C18:
Product Code | Product Name | Product Description |
G5CX0C | Guard Cartridge 5CX-C18 | 5um,ODS, Polar End-Capping (5x1mm), 3pcs |
G5CX0M | Guard Cartridge 5CX-C18 | 5um,ODS, Polar End-Capping (10x8mm), 2pcs |
G5CX0S | Guard Cartridge 5CX-C18 | 5um,ODS, Polar End-Capping (5x2mm), 3pcs |
GCH01S | Guard Holder | Guard Holder for 1-6mmI.D. separation columns |
GCH02M | Guard Holder | Guard Holder for 10-20mmI.D. separation columns |
GCH11S | Guard Holder | Guard Holder for 4.6mm column, enclosed an U-Shape column coupler |
GCH12M | Guard Holder | Guard Holder for 10-20mm column, enclosed an U-Shape column coupler |
All stationary phases can also be made in the following internal diameters, please contact our Sales Team with your specificatons: Nano: 0.02mm, 0075mm | Capillary: 0.1mm, 0.3mm, 0.5mm | Semi-Prep: 20mm, 28mm
This column is also available in particle size 3µm!
Additional Imtakt Columns Available
- Model: 5CX075
- Manufactured by: Imtakt