Cadenza 5CX-C18 Polar End-Capping ODS Column
Cadenza 5CX-C18 Polar End-Capping 75mm x 6mm, 5μm, 120Å, Semi-preparative HPLC Column, Pressure limits of up to: 20MPa, 250 bar, 3,000 psi
Imtakt Product Number 5CX063
Column Specifications:
| Base Material: |
Silica |
| Quantity: |
1 piece |
| Chemistry: |
C18 (RP-18, ODS, Octadecyl) |
| Manufacturer Chemistry Name: |
5CX-C18 |
| Endcapping: |
Polar End Capping |
| Matrix: |
Silica |
| Brand: |
Imtakt Cadenza |
| Internal Diameter: |
6 mm |
| Length: |
75 mm |
| Particle Morphology: |
spherical, porous |
| Particle Size: |
5 μm |
| Pressure Stability: |
up to 250 bar |
| Pore Size: |
120 Å |
| Technology: |
HPLC |
| pH: |
2-10 |
| MW: |
up to 10 kDa |
| USP Class: |
L1 |
High steric selectivity and molecular recognition C18 column for general use, ideal for separation of
isomers and other difficult to separate compounds. Polar end-capping technology provides a more complete coverage of surface silanols and unique selectivity.
Conventional ODS columns, including hybrid-silica type columns, require extensive end-capping in order to decrease residual silanols, which may negatively affect peak shape for basic compounds. Traditionally, this end-capping process has used methyl silane compounds which have a mild hydrophobic interaction. Viewing this interaction in terms of reversed-phase mode, the surface of the stationary phase presents two very different kinds of hydrophobic structures, octadecyl ligands (C18) and the methyl end-capping. These different hydrophobicities may provide an inconsistent response against a solutes interaction with the stationary phase, resulting in poor peak shape and reduced plate counts. Instead of relying on traditional end-capping with trimethyl silane (TMS) compounds, we have succeeded to develop a revolutionary surface modification technology using alcohol structures, which has been adapted to our brand new Cadenza CX-C18. This means that electrostatic interaction from the polar end-capped surface and hydrophobic interaction from the C18 ligand will localize the polarity of the surface and increase the recognition power of a complex compounds hydrophobic/hydrophilic structure. Therefore, Cadenza CX-C18 will have an alternative selectivity for certain compounds and possibly improved peak shape compared to conventional end-capped ODS columns.
- Imtakt's first column featuring modified alcohol polar end-capping
- Nearly 100% coverage of active surface silanol sites
- Reduces tailing for basic compounds in acidic conditions
- Alternative selectivity from traditional C18 columns
- High steric selectivity and molecular recognition
- Ideal for difficult isomer or impurity separations
Range of Cadenza 5CX-C18 Columns, Product Numbers:
Column Guard System for Cadenza 5CX-C18:
| Product Code |
Product Name |
Product Description |
| G5CX0C |
Guard Cartridge 5CX-C18 |
5um,ODS, Polar End-Capping (5x1mm), 3pcs |
| G5CX0M |
Guard Cartridge 5CX-C18 |
5um,ODS, Polar End-Capping (10x8mm), 2pcs |
| G5CX0S |
Guard Cartridge 5CX-C18 |
5um,ODS, Polar End-Capping (5x2mm), 3pcs |
| GCH01S |
Guard Holder |
Guard Holder for 1-6mmI.D. separation columns |
| GCH02M |
Guard Holder |
Guard Holder for 10-20mmI.D. separation columns |
| GCH11S |
Guard Holder |
Guard Holder for 4.6mm column, enclosed an U-Shape column coupler |
| GCH12M |
Guard Holder |
Guard Holder for 10-20mm column, enclosed an U-Shape column coupler |
All stationary phases can also be made in the following internal diameters, please contact our Sales Team with your specificatons: Nano: 0.02mm, 0075mm | Capillary: 0.1mm, 0.3mm, 0.5mm | Semi-Prep: 20mm, 28mm
This column is also available in particle size 3µm!
Additional Imtakt Columns Available
