Imtakt Cadenza CX-C18 10mm ID, 250mm Length, 3um,ODS, Polar End-Capping - CX0P6

Cadenza CX-C18 Polar End-Capping ODS Column

Cadenza CX-C18 Polar End-Capping 250mm x 10mm, 3μm, 120Å, Semi-preparative HPLC Column, Pressure limits of up to: 20MPa, 250 bar, 3,000 psi

Imtakt Product Number CX0P6

Column Specifications:

High steric selectivity and molecular recognition C18 column for general use, ideal for separation of
isomers and other difficult to separate compounds. Polar end-capping technology provides a more complete coverage of surface silanols and unique selectivity.

Conventional ODS columns, including hybrid-silica type columns, require extensive end-capping in order to decrease residual silanols, which may negatively affect peak shape for basic compounds. Traditionally, this end-capping process has used methyl silane compounds which have a mild hydrophobic interaction. Viewing this interaction in terms of reversed-phase mode, the surface of the stationary phase presents two very different kinds of hydrophobic structures, octadecyl ligands (C18) and the methyl end-capping. These different hydrophobicities may provide an inconsistent response against a solutes interaction with the stationary phase, resulting in poor peak shape and reduced plate counts. Instead of relying on traditional end-capping with trimethyl silane (TMS) compounds, we have succeeded to develop a revolutionary surface modification technology using alcohol structures, which has been adapted to our brand new Cadenza CX-C18. This means that electrostatic interaction from the polar end-capped surface and hydrophobic interaction from the C18 ligand will localize the polarity of the surface and increase the recognition power of a complex compounds hydrophobic/hydrophilic structure. Therefore, Cadenza CX-C18 will have an alternative selectivity for certain compounds and possibly improved peak shape compared to conventional end-capped ODS columns.

• Imtakt's first column featuring modified alcohol polar end-capping
• Nearly 100% coverage of active surface silanol sites
• Reduces tailing for basic compounds in acidic conditions
• Alternative selectivity from traditional C18 columns
• High steric selectivity and molecular recognition
• Ideal for difficult isomer or impurity separations

Range of Cadenza CX-C18 Columns, Product Numbers:

Column Guard System for Cadenza CX-C18:

All stationary phases can also be made in the following internal diameters, please contact our Sales Team with your specificatons: Nano: 0.02mm, 0075mm | Capillary: 0.1mm, 0.3mm, 0.5mm | Semi-Prep: 20mm, 28mm

This column is also available in particle size 5µm!

• Imtakt Cadenza 5CX-C18