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Imtakt Cadenza CX-C18 6mm ID, 100mm Length, 3um,ODS, Polar End-Capping - CX064

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Cadenza CX-C18 Polar End-Capping ODS Column

Cadenza CX-C18 Polar End-Capping 100mm x 6mm, 3μm, 120Å, Semi-preparative HPLC Column, Pressure limits of up to: 20MPa, 250 bar, 3,000 psi

Imtakt Product Number CX064

Column Specifications:

Base Material: Silica
Quantity: 1 piece
Chemistry: C18 (RP-18, ODS, Octadecyl)
Manufacturer Chemistry Name:  CX-C18
Endcapping: Polar End Capping
Matrix: Silica
Brand: Imtakt Cadenza
Internal Diameter: 6 mm  
Length: 100 mm  
Particle Morphology: spherical, porous
Particle Size: 3 μm
Pressure Stability: up to 250 bar
Pore Size: 120 Å
Technology: HPLC
pH: 2-10
MW: up to 10 kDa
USP Class: L1

High steric selectivity and molecular recognition C18 column for general use, ideal for separation of
isomers and other difficult to separate compounds. Polar end-capping technology provides a more complete coverage of surface silanols and unique selectivity.

Conventional ODS columns, including hybrid-silica type columns, require extensive end-capping in order to decrease residual silanols, which may negatively affect peak shape for basic compounds. Traditionally, this end-capping process has used methyl silane compounds which have a mild hydrophobic interaction. Viewing this interaction in terms of reversed-phase mode, the surface of the stationary phase presents two very different kinds of hydrophobic structures, octadecyl ligands (C18) and the methyl end-capping. These different hydrophobicities may provide an inconsistent response against a solutes interaction with the stationary phase, resulting in poor peak shape and reduced plate counts. Instead of relying on traditional end-capping with trimethyl silane (TMS) compounds, we have succeeded to develop a revolutionary surface modification technology using alcohol structures, which has been adapted to our brand new Cadenza CX-C18. This means that electrostatic interaction from the polar end-capped surface and hydrophobic interaction from the C18 ligand will localize the polarity of the surface and increase the recognition power of a complex compounds hydrophobic/hydrophilic structure. Therefore, Cadenza CX-C18 will have an alternative selectivity for certain compounds and possibly improved peak shape compared to conventional end-capped ODS columns.

  • Imtakt's first column featuring modified alcohol polar end-capping
  • Nearly 100% coverage of active surface silanol sites
  • Reduces tailing for basic compounds in acidic conditions
  • Alternative selectivity from traditional C18 columns
  • High steric selectivity and molecular recognition
  • Ideal for difficult isomer or impurity separations

Range of Cadenza CX-C18 Columns, Product Numbers:

Column Length (mm) Analytical Semi-prep
1.0 mm I.D. 1.5 mm I.D. 2.0 mm I.D. 3.0 mm I.D. 4.6 mm I.D. 6.0 mm I.D. 10.0 mm I.D.
3µm Columns, Pressure limits of up to: 20MPa, 250 bar, 3,000 psi
10     CX020 CX030 CX000    
20     CX029 CX039 CX009    
30 CX011 CX071 CX021 CX031 CX001 CX061 CX0P1
50 CX012 CX072 CX022 CX032 CX002 CX062 CX0P2
75 CX013 CX073 CX023 CX033 CX003 CX063 CX0P3
100 CX014 CX074 CX024 CX034 CX004 CX064 CX0P4
150 CX015 CX075 CX025 CX035 CX005 CX065 CX0P5
250 CX016 CX076 CX026 CX036 CX006 CX066 CX0P6
          CX007    
3µm HT Columns, Pressure limits of up to: 50M Pa, 500 bar, 7,500 psi
10     CX020T CX030T   CX000T  
20     CX029T CX039T   CX009T  
30 CX011T CX071T CX021T CX031T   CX001T  
50 CX012T CX072T CX022T CX032T   CX002T  
75 CX013T CX073T CX023T CX033T   CX003T  
100 CX014T CX074T CX024T CX034T   CX004T  
150 CX015T CX075T CX025T CX035T   CX005T  
250 CX016T CX076T CX026T CX036T   CX006T  
3µm UHPLC (UP) Columns, Pressure limits of up to: 10M Pa, 1000 bar, 15,000 psi
30     CX021U        
50     CX022U        
75     CX023U        
100     CX024U        
150     CX025U        
250     CX026U        
3µm Metal-Free Columns, Pressure limits of up to: 50MPa, 500bar, 7,500psi
30     CX021F        
50     CX022F        
75     CX023F        
100     CX024F        
150     CX025F        
250     CX026F        

Column Guard System for Cadenza CX-C18:

Product Code Product Name Product Description
GCCX0C Guard Cartridge CX-C18 3um,Hybrid ODS,end-capped (5x1mm), 3pcs
GCCX0M Guard Cartridge CX-C18 3um,Hybrid ODS,end-capped (10x8mm), 2pcs
GCCX0S Guard Cartridge CX-C18 3um,Hybrid ODS,end-capped (5x2mm), 3pcs
GCH01S Guard Holder Guard Holder for 1-6mmI.D. separation columns
GCH02M Guard Holder Guard Holder for 10-20mmI.D. separation columns
GCH11S Guard Holder Guard Holder for 4.6mm column, enclosed an U-Shape column coupler
GCH12M Guard Holder Guard Holder for 10-20mm column, enclosed an U-Shape column coupler

All stationary phases can also be made in the following internal diameters, please contact our Sales Team with your specificatons: Nano: 0.02mm, 0075mm | Capillary: 0.1mm, 0.3mm, 0.5mm | Semi-Prep: 20mm, 28mm

This column is also available in particle size 5µm!


  • Model: CX064
  • Manufactured by: Imtakt

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